5398-79-8

Usage

Uses

Used in Pharmaceutical Industry:
Benzeneacetic acid, 2,5-dichloro-, is used as a chemical intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties. Benzeneacetic acid, 2,5-dichloro-'s reactivity and functional groups make it a valuable building block in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, Benzeneacetic acid, 2,5-dichloro-, serves as a precursor for the production of various agrochemicals, including herbicides and pesticides. Its chemical properties enable the creation of effective compounds that can protect crops from pests and diseases, thereby increasing agricultural productivity.
Used in Chemical Research:
Benzeneacetic acid, 2,5-dichlorois also utilized in chemical research for studying the effects of halogen substitution on the properties and reactivity of benzeneacetic acid derivatives. Research in this area can lead to the discovery of new compounds with improved properties and applications in various fields.

InChI:InChI=1/C8H6Cl2O2/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3H,4H2,(H,11,12)

Upstream product

• 85482-13-9 2,5-dichlorobenzylbromide 
• 2745-49-5 1,4-Dichloro-2-chloromethyl-benzene 
• 34145-05-6 2,5-dichlorobenzyl alcohol 
• 67643-08-7 4-[(2,5-dichloro-phenyl)-thioacetyl]-morpholine 
• 3218-50-6 2-(2,5-dichlorophenyl)acetonitrile 
• 96129-66-7 methyl 2-(2,5-dichlorophenyl)acetate 

Downstream Products

• 203314-48-1 (2,5-dichloro-phenyl)-acetyl chloride 
• 1445985-27-2 ethyl 5-[(2,5-dichlorophenyl)methyl]-1,3-oxazole-4-carboxylate 
• 1445982-03-5 1-cyclopropyl-4-([5-[(2,5-dichlorophenyl)methyl]-1,3-oxazol-4-yl]carbonyl)-1,2,3,4-tetrahydroquinoxaline 
• 1445985-28-3 5-[(2,5-dichlorophenyl)methyl]-1,3-oxazole-4-carboxylic acid 
• 407637-64-3 N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}2-(2,5-dichlorophenyl)acetamide 

Relevant academic research and scientific papers

ANTI-HCMV COMPOSITIONS AND METHODS

This document relates to compounds useful as agents for preventing or treating human cytomegalovirus (HCMV) infections.

NON-SYSTEMIC TGR5 AGONISTS

Compounds of structure (I), or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, R3, R4, R8, R9, R10, R11, R12, A1, A2, X, Y and Z are as defined herein. Uses of such compounds as TGR5 antagonists and for treatment of various indications, including Type II diabetes meletus are also provided.

FUNGICIDAL MIXTURES

Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1 N-oxides, and salts thereof, insert Formula 1 here wherein R1, R2, A, G, Q, W1, W2, X and n are otherwise as defined in the disclosure, and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of the aforesaid composition.

FUNGICIDAL CARBOXAMIDES

This invention is directed to compounds of Formula (1) including all geometric and stereoisomers, N oxides, and agriculturally suitable salts thereof, agricultural compositions containing them and their use as fungicides, ( l ) provided that the compound of Formula 1 is other than 2-[1-[(2-chlorophenyl)acetyl]-4-piperidinyl]-N-methyl-N-[(1R)-1-phenylethyl]-4-thiazolecarboxamide and R1 is other than 4-fluorophenyl; wherein R1, R2, A, G, Q, W1, W2, X and n are otherwise as defined in the disclosure, Also disclosed are compositions containing the a compound having a formula corresponding to Formula 1 where the provisos are both omitted; and methods for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound having a formula corresponding to Formula (1) where the provisos are both omitted.

2- and 2,5-substituted phenylketoenols

The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) in which Het represents one of the groups ?in which A, B, D, G, X and Z are each as defined in the description, to a plurality of processes and intermediates for their preparation, and to their use as pesticides.

METABOLISM OF CHLOROPHENYLALANINES IN CROP AND WEED PLANTS IN RELATION TO THE FORMATION OF POTENTIAL HERBICIDAL END PRODUCTS

Metabolism of 12 synthetic D,L-chlorophenylalanines has been examined in several crop and weed plants.Twenty-five gram samples of excised shoots or leaves of bushbean, soybean, corn, pigweed, lambsquarters, and giant foxtail were allowed to metabolize 10-4 M solutions of the D,L-chlorophenylalanines for 24 hr in continuous light.The plant samples were then extracted in 80percent methanol and the soluble acidic metabolites fractionated into ether.Each ether concentrate was partially purified by fractional elution from a PrepSep C18 coloumn and then analysed by HPLC.Collected fractions were esterified with pentafluorobenzylbromide and examined by GC-MS to demonstrate the presence of PFB-esters of chlorophenylacetic, chlorobenzoic and/or chlorocinnamic acids.Since certain of these metabolites are known to be potent plant growth-regulators and herbicides, the results are discussed in relation to the potantial herbicidal action of certain chlorophenylalanines by the mechanism of 'lethal synthesis'.Key Word Index - Phaseolus vulgaris; Glycine max.; Leguminosae; Zea mays; Amaranthus retroflexus; Chenopodium album; Setaria faberii; metabolism; D,L-chlorophenylalanines; chlorophenylacetic acids; chlorobenzoic acids; chlorocinnamic acids; growth regulators.