54004-38-5

Basic information

• Product Name: 7-methylisoquinoline
• Synonyms: 7-Methylisoquinoline;Einecs 258-913-7;7-Methylisoquinoline ,97%;Isoquinoline, 7-methyl-
• CAS NO: 54004-38-5
• Molecular Formula: C₁₀H₉N
• Molecular Weight: 143.18
• EINECS: 258-913-7
• Product Categories: Isoquinoline Derivertives
• Mol File: 54004-38-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 67-68 °C
• Boiling Point: 245.7°Cat760mmHg
• Flash Point: 99.7°C
• Appearance: /
• Density: 1.076g/cm³
• Vapor Pressure: 0.0443mmHg at 25°C
• Refractive Index: 1.624
• PKA: 5.63±0.10(Predicted)
• CAS DataBase Reference: 7-methylisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methylisoquinoline(54004-38-5)
• EPA Substance Registry System: 7-methylisoquinoline(54004-38-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 54004-38-5(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow crystalline powder

InChI:InChI=1/C10H9N/c1-8-2-3-9-4-5-11-7-10(9)6-8/h2-7H,1H3

Upstream product

• 7480-80-0 5-methyl-1H-indene 
• 99060-14-7 N-(2-oxo-2-(p-tolyl)ethyl)formamide 
• 24188-80-5 1-chloro-7-methylisoquinoline 
• 10034-85-2 hydrogen iodide 
• 102014-89-1 formic acid-(β-hydroxy-4-methyl-phenethylamide) 

Downstream Products

• 87087-20-5 isoquinoline-7-carboxaldehyde 
• 1338322-23-8 (S)-phenyl 1-((S)-2-(4-methoxyphenyl)-4-methyl-5-oxo-4,5-dihydrooxazol-4-yl)-7-methylisoquinoline-2(1H)-carboxylate 

Relevant articles and documents

Synthesis of Isoquinolines from Indenes

A general procedure for the synthesis of isoquinolines from appropriately substituted indenes is described.Ozonolysis of the indenes followed by reductive workup gives intermediate homophthalaldehydes which are treated with ammonium hydroxide to give the isoquinolines.This "one-pot", three-step reaction sequence was applied to the formation of all of the mono-C-methyl-substituted isoquinolines in a regiospecific manner.The procedure is applicable to both electron-withdrawing and electron-donating substituents on the indene system.In this manner the 6- and 7-nitro-,-bromo-, and -iodoisoquinolines were prepared.