54019-08-8

Upstream product

• 108-24-7 acetic anhydride 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 830-03-5 4-nitrophenol acetate 
• 121-98-2 methyl 4-methoxybenzoate 
• 75-36-5 acetyl chloride 

Downstream Products

• 40746-65-4 5-methyl-1-(4-nitrophenyl)-1H-tetrazole 
• 82020-14-2 3-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole 
• 25877-54-7 methyl 4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl ether 
• 25877-53-6 2-(4-methylphenyl)-5-methyl-1,3,4-oxadiazole 
• 59105-35-0 3-acetyl-5-(4-methoxy-phenyl)-3H-[1,2,3,4]oxathiadiazole 2-oxide 

Relevant academic research and scientific papers

Reactivity of benzohydrazide derivatives towards acetylation reaction. Experimental and theoretical studies

We herein report an experimental and theoretical study on the acetylation reaction of benzohydrazide derivatives towards p-nitrophenyl acetate (NPA). The kinetic data are consistent with a stepwise mechanism with the nucleophilic attack as the rate determining step. From the theoretical analysis it is found that benzohydrazide derivatives establish intramolecular proton rearrangement. The enol form appears as the active species for nucleophilic attack. A reaction mechanism incorporating keto-enol pre-equilibria is proposed. The study is completed with a local reactivity analysis describing the most reactive centers for nucleophilic attack together with a site activation analysis describing inductive substituent effects.

Near-infrared-absorbing organic electrochromic materials

The invention provides generally a new type of organic electrochromic Near Infrared (NIR)-active materials capable of absorbing and attenuating the light in the NIR region around 1550 nm and forming thin films on electrodes for variable optical attenuator

Synthesis and spectral properties of 2-methyl-5-aryl-1,3,4-oxadiazoles

By heterocyclization of 1-acyl-2-aroylhydrazines under the influence of strong dehydrating substances, a series of 2-methyl-5-aryl-1,3,4-oxadiazoles has been synthesized and their UV, IR, and PMR spectra have been investigated. Through analysis of data on

Synthesis and analgesic activity in 1,2,4-triazole series

Derivatives of 1,2,4-triazole have been synthesized. Several methods of synthesis were used and the analgetic and antiinflammatory properties of the products obtained were studied. Structural requirements for analgetic activity were specified. Certain compounds show a high degree of analgetic activity. One of them, RU 39813, has been chosen for extended pharmacological study.