40746-65-4

Basic information

• Product Name: 5-methyl-1-(4-nitrophenyl)-1H-tetrazole
• Synonyms: 1H-Tetrazole, 5-methyl-1-(4-nitrophenyl)-; 5-Methyl-1-(4-nitrophenyl)-1H-tetrazole
• CAS NO: 40746-65-4
• Molecular Formula: C₈H₇N₅O₂
• Molecular Weight: 205.1735
• Mol File: 40746-65-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 410°C at 760 mmHg
• Flash Point: 201.8°C
• Density: 1.53g/cm³
• Vapor Pressure: 6.22E-07mmHg at 25°C
• Refractive Index: 1.721
• CAS DataBase Reference: 5-methyl-1-(4-nitrophenyl)-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-(4-nitrophenyl)-1H-tetrazole(40746-65-4)
• EPA Substance Registry System: 5-methyl-1-(4-nitrophenyl)-1H-tetrazole(40746-65-4)

Safety Data

• Hazardous Substances Data: 40746-65-4(Hazardous Substances Data)

Upstream product

• 100-19-6 (4-nitrophenyl)ethanone 
• 14213-16-2 5-methyl-1-phenyl-1H-tetrazole 
• 934168-30-6 N-(1-chloroethylidene)-4-nitrobenzenamine 
• 4076-36-2 5-methyl-1,2,3,4-tetrazole 
• 350-46-9 4-Fluoronitrobenzene 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 186818-30-4 N’-acetyl-4-methylbenzohydrazide 
• 82122-73-4 N-acetyl-N'-phenylacetylhydrazine 
• 54019-08-8 4-methoxy-benzoic acid N'-acetyl-hydrazide 
• 22815-97-0 N’-acetyl-4-chlorobenzohydrazide 
• 14368-49-1 p-nitrobenzenediazonium 
• 500890-29-9 N’-acetyl-4-(dimethylamino)benzohydrazide 

Downstream Products

• 49819-79-6 1,2-dimethyl-5-nitro-1H-benzimidazole 
• 19492-66-1 1,2-dimethyl-6-nitro-1H-benzoimidazole 
• 1821-27-8 N,N-bis(p-nitrophenyl)amine 
• 100-01-6 4-nitro-aniline 
• 1792-40-1 6-nitro-2-methyl-1H-benzimidazole 
• 100-15-2 N-methyl(p-nitroaniline) 
• 1194641-40-1 3-(4-methylphenyl)-5-(5-methyl-1H-tetrazol-1-yl)-2,1-benzisoxazole 
• 1083223-71-5 5-(5-methyl-1H-tetrazol-1-yl)-3-phenyl-2,1-benzisoxazole 
• 1083403-33-1 3-(4-chlorophenyl)-5-(5-methyl-1H-tetrazol-1-yl)-2,1-benzisoxazole 

Relevant articles and documents

An efficient synthesis of nitrile, tetrazole and urea from carbonyl compounds

An efficient conversion of carbonyl compounds (aldehydes and ketones) to nitrile, tetrazole, and urea was developed with the use of a POCl3 and sodium azide mixture using a convergent and microwave method. This is the first report on the direct conversion of ketone to urea. The synthesized compounds were characterized by 1H NMR, 13C NMR, mass and IR spectroscopies and were found to be in agreement with reported compounds.

Microwave-assisted arylation of 5-substituted tetrazoles

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SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

Substituted cyclopropyl compounds of formula (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.