54022-58-1

Upstream product

• 143-33-9 sodium cyanide 
• 88775-45-5 (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(3,4-dimethoxyphenyl)-2-propen-1-one 
• 151-50-8 potassium cyanide 
• 6329-73-3 1-benzo[1,3]dioxol-5-yl-ethanol 
• 3162-29-6 1-(benzo[d][1,3]dioxol-6-yl)ethanone 
• 120-57-0 piperonal 

Downstream Products

• 105594-89-6 2-(3,4-dimethoxyphenyl)-6,7-methylenedioxy-1-(N-methylformamido)naphthalene 
• 105594-81-8 cis-2-(3,4-dimethoxyphenyl)-N-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydro-1-naphthylamine 
• 88114-55-0 2-(3,4-dimethoxyphenyl)-6-hydroxy-7-methoxy-1-(N-methylformamido)naphthalene 
• 52259-64-0 fagaronine 
• 13063-04-2 nitidine chloride 
• 41303-46-2 2-(3,4-dimethoxyphenyl)-6,7-methylenedioxy-3,4-dihydronaphthalen-1(2H)-one 
• 88775-39-7 2-(3,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxobutyramide 
• 41303-68-8 2-(3,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-4-oxobutyric acid 
• 54022-59-2 2-(3,4-dimethoxyphenyl)-4-(3',4'-methylenedioxyphenyl) butyric acid 

Relevant academic research and scientific papers

Studies on the chemical constituents of rutaceous plants. XLIX. Development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (1). Preparation of various 2,4-bisaryl-4-oxobutyronitriles and 2,4-bisaryl-4-oxobutyramides

For the sake of establishment of a versatile synthetic method for benzo[c]phenanthridine alkaloids, improvement of the Robinson synthetic method was examined. Thirteen chalcones (7a-m) were prepared by condensation of two acetophenone derivatives (15 and 16) with eleven benzaldehyde derivatives (19a-k) as fundamental starting materials. Hydrocyanation of these chalcones (7a-1) except one (7m) gave the corresponding 2,4-bisaryl-4-oxobutyronitriles (8a-1). Eleven 2,4-bisaryl-4-oxobutyramides (9a-k) were also prepared.