54026-27-6Relevant articles and documents
Reaction of Oximes with Dimethyl Carbonate: A New Entry to 3-Methyl-4,5-disubstituted-4-oxazolin-2-ones
Marques, C. A.,Selva, M.,Tundo, P.,Montanari, F.
, p. 5765 - 5770 (2007/10/02)
The reaction of ketone oximes with dimethyl carbonate (DMC) carried out in an autoclave at 180-190 deg C and in the presence of K2CO3 yields 3-methyl-4,5-disubstituted-4-oxazolin-2-ones.The reaction can be applied to both aliphatic and aromatic ketone oximes, provided that a methylene group be present near the C=N bond.Nonoptimized yields range from 22 to 48percent.The reaction seems to be a sigmatropic rearrangement where DMC plays a key role in causing the initial N-methylation of the oximes.
On the reactions of oxazolium salts with dialkyl acylphosphonates. A novel synthesis of 1,4 oxazin 3 one and azetidin 2 one derivatives
Takamizawa,Sato
, p. 1526 - 1541 (2007/10/04)
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