54053-76-8

Upstream product

• 15753-50-1 cis-1,2-cyclohexanedimethanol 
• 2484-60-8 cyclohexane-1,2-dicarboxylic acid monomethyl ester 
• 3205-36-5 trans-1,2-bis(hydroxymethyl)cyclohexane di-p-toluene-sulfonate 
• 76155-27-6 (+/-)-trans-2-(hydroxymethyl)cyclohexylmethanol 
• 96836-97-4 diethyl cyclohexane-trans-1,2-dicarboxylate 
• 4841-85-4 trans-1,2-bis(ethoxycarbonyl)-4-cyclohexene 
• 3710-30-3 1,7-Octadiene 
• 13019-30-2 trans-1,2-bis(bromomethyl)cyclohexane 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 59461-66-4 cis-cyclohexane-1,2-diyldimethyl ditosylate 
• 13019-30-2 (±)-1,2-bis(bromomethyl)cyclohexane 

Downstream Products

• 92278-01-8 (3aR,7aS)-2-(2,5-Dihydroxy-phenyl)-octahydro-benzo[c]thiophenium; chloride 

Relevant academic research and scientific papers

Metallacycle transfer from zirconium to main group elements: A versatile synthesis of heterocycles

The reaction of zirconium metallacycles is used to produce a variety of main group heterocycles including borole Diels-Alder dimers, galloles, indacyclopentadienes, siloles, germoles, stannoles, phospholes, arsoles, stiboles, bismoles, thiophenes, selenophenes, dihydrothiophenes, dihydroselenophenes, tetrahydrothiophenes, tetrahydro-selenophenes, stannacyclopentanes, phospholenes, and isothiazoles. An X-ray crytallographic study of the borole DielsAlder dimer of 1-phenyl-2,3,4,5-tetramethylborole is discussed and compared with the structure of 7-norbornenyl carbenium ions. The scope and potential for this metallacycle transfer reaction are delineated.

SYNTHESIS OF 1-SUBSTITUTED trans-2-THIAHYDRINDANES AND 3-SUBSTITUTED trans-2-THIADECALINS

Methods of synthesis of 1-R-trans-2-thiahydrindanes and 3-R-trans-2-thiadecalins from trans-1-methoxymethyl-2-chlorocyclohexane have been developed.The order of the chromatographic elution of the isomeric sulfides formed has been found.The configurations

Conformational Equilibrium in 8-Methyl-cis-2-thiahydrindane and 8-Methyl-cis-2-oxahydrindane by 13C NMR Spectroscopy

The preferred conformation of 8-methyl-cis-thiahydrindane has been both estimated by 13C NMR chemical shifts and determined by low temperature 13C NMR spectroscopy to be the conformer with the methyl group equatorial with respect to the cyclohexane ring.This result is in disagreement with the interpretation of the temperature dependence of the CD spectra of (+) and (-) 8-methyl-cis-2-thiahydrindane, whereby the conformation with the methyl group axial with respect to the cyclohexane ring was claimed to be the preferred conformation.The preferred conformation of the related oxygen heterocycle, 8-methyl-cis-2-oxahydrindane, has been estimated by 13C NMR chemical shifts to be the conformer with the methyl group axial with respect to the cyclohexane ring.Possible reasons for these observations are discussed.

Reactions of α-Halotetrahydrothiophene 1,1-Dioxides with Strong Bases

This article describes the halogenated sulfones 2, 3, 7, 11, 16 and 18 obtained from the hitherto unknown intermediates 4, 5, 6 and 8, 9, 10 and from 14, 15.An account is given of Ramberg-Baecklund-type reactions undergone by the α-halogenated cyclic sulfones 2a and 7 with bases at high temperature.