54064-40-3Relevant academic research and scientific papers
Synthesis and structure of nitrocyclohexenylcarboxylates
Anisimova,Kuzhaeva,Berkova,Berestovitskaya
experimental part, p. 1845 - 1852 (2012/01/07)
The diene condensation of 3-nitro- and 3-bromo-3-nitroacrylates with 2,3-dimethyl-1,3-butadiene and isoprene obtained under the reaction condition from 3-methyl-3-thiolene-1,1-dioxide was investigated. The formed 6-nitro-3-cyclohexenylcarboxylates were subjected to the intramolecular transformation (dehydration and dehydrohalogenation) to give the corresponding nitrocyclohexadienyl- and arylcarboxylates. The structure of the obtained compounds was established from the IR, 1H NMR spectra and independent synthesis.
NOVEL ANTI-INFLAMMATORY AGENTS
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Page/Page column 80-82, (2010/11/05)
Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.
Synthesis of symmetric diester-functionalised Troeger's base analogues
Bhuiyan, M. Delower H.,Zhu, Kai-Xian,Jensen, Paul,Try, Andrew C.
supporting information; experimental part, p. 4662 - 4670 (2010/10/19)
The yields of ester-functionalised Troeger's base analogues are dramatically improved by incorporating an electron-donating group on the aromatic ring and/or enhancing solubil- ity of the aniline unit. In addition to 2,8-diester compounds, 1,7-, 3,9- and 4,10-diester-functionalised Troeger's base analogues have been prepared for the first time.
