54074-17-8Relevant articles and documents
PREPARATION AND PROPERTIES OF POLYMERS ANCHORING BIPHENYL-2-OL.
Ishikawa
, p. 2177 - 2178 (1983)
The monomer, 2-biphenyl acrylate (BPA) was prepared and was polymerized and copolymerized with vinyl acetate (VAc), styrene and N-vinylpyrrolidone. The reactivity ratios of BPA(M//1) with VAc were evaluated as r//1 equals 4. 6 plus 0. 4 and r//2 equals 0. 37 plus 0. 08. The polymers were hydrolyzed in methanol-phosphate buffer solution (pH 6 and 8), and the release rate of biphenyl-2-ol from the polymer was investigated. The biphenyl-2-ol could thus be employed as a fungicide over an extended period.
Enzymatic Esterolysis of Polymers Containing 2-Biphenylyl Ester Bonds in Side Chains
Ishikawa, Tomomichi,Otsuki, Makoto,Iwatsuki, Toshiaki
, p. 3621 - 3624 (2007/10/02)
The preparation and α-chymotrypsin-catalyzed esterolysis of polymeric substrates anchoring fungicidal biphenyl-2-ol are described.In order to obtain information regarding the influence of one type of polymeric backbone and the distance between a cleavable bond and a polymer main chain, poly(2-biphenylyl acrylate), poly(2-biphenylyl methacrylate), and poly(methacryloylamino acid 2-biphenylyl ester) were studied.The esterolysis were evaluated by means of Michaelis constant Km and the catalytic reaction rate constant kcat.Poly(2-biphenylyl methacrylate) was a more suitable substrate than poly(2-biphenylyl acrylate).Poly was the most suitable substrate in a series of polymers containing amino acid side chains with 2-biphenylyl ester terminal groups.The release rate of biphenyl-2-ol could also be controlled by using copolymers with an appropriate comonomer.