540752-88-3

Upstream product

• 540752-87-2 tert-butyl 4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-carboxylate 
• 56-05-3 2-Amino-4,6-dichloropyrimidine 
• 571202-87-4 3-bromophenyl triisopropylsilyl ether 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 862261-23-2 4-(3-triisopropylsilanyloxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 540752-86-1 4-(3-trifluoromethanesulfonyloxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 198627-86-0 1,1-dimethylethyl 4-(3-hydroxyphenyl)-1-piperazinecarboxylate 

Downstream Products

• 540751-83-5 4-[3-(5-amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester 
• 540752-08-7 2-furan-2-yl-7-(3-piperazin-1-yl-phenyl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine 

Relevant academic research and scientific papers

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: The successful reduction of hERG activity. Part 2

The structure-activity relationship (SAR) exploration using 2-(2-furanyl)-7-phenyl[1,2,4]triazolo-[1,5-c]pyrimidin-5-amine (1) as a template led to the identification of a novel class of potent and selective adenosine A2A receptor (AR) antagoni