540778-82-3Relevant academic research and scientific papers
BF3·OEt2-mediated: Syn -selective Meyer-Schuster rearrangement of phenoxy propargyl alcohols for Z -β-aryl-α,β-unsaturated esters
Puri, Surendra,Hari Babu, Madala,Sridhar Reddy, Maddi
, p. 7001 - 7009 (2016/07/30)
Synthesis of Z-β-aryl-α,β-unsaturated esters from readily available 1-aryl-3-phenoxy propargyl alcohols is achieved via a BF3-mediated syn-selective Meyer-Schuster rearrangement under ambient conditions. The reaction mechanism is postulated to involve an electrophilic borylation of an allene intermediate as the key step to kinetically control the stereoselectivity.
An improved preparation of mesoporous silica-supported Pd as sustainable catalysts for phosphine-free Suzuki-Miyaura and Heck coupling reactions
Basu, Basudeb,Paul, Susmita
, p. 588 - 594 (2013/10/21)
An improved and eco-friendly procedure has been developed to generate mesoporous silica-supported palladium nanoparticles (SiO2@PdNP) that could be used as a sustainable heterogeneous Pd catalyst for phosphine-free Suzuki-Miyaura and Heck coupling reactions with excellent turnover number and turnover frequency. The presence of Pd on the silica surface was detected by X-ray diffraction and the structural morphology of SiO2@PdNP was obtained by transmission electron microscopy. The heterogeneous catalytic system is recyclable and leaching of the metal after the reaction is not apparently observed. Copyright
Palladium supported on a polyionic resin as an efficient, ligand-free, and recyclable catalyst for Heck, Suzuki-Miyaura, and Sonogashira reactions
Basu, Deb,Das, Sajal,Das, Pralay,Mandal, Bablee,Banerjee, Dipanjan,Almqvist, Fredrik
experimental part, p. 1137 - 1146 (2009/12/01)
Polyionic Amberlite resin formate (ARF), derived from commercially available Amberlite resin chloride by simple rinsing with aqueous formic acid, could be soaked with palladium(0) from palladium salts, the formate counteranion being the reducing source. The resulting Amberlite resin formate supported with palladium(0), ARF-Pd, showed excellent catalytic activity in Heck, Suzuki-Miyaura, and Sonogashira couplings with a range of substrates. The catalyst may be recovered easily and quantitatively without leaching and recycled; it was tested for five runs without any significant loss of activity. Georg Thieme Verlag Stuttgart.
Induction of apoptosis in cancer cells
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, (2008/06/13)
The present invention provides compounds that are inducers or inhibitors of apoptosis or apoptosis preceded by cell-cycle arrest. In addition, the present invention provides pharmaceutical compositions and methods for treating mammals with leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells.
