54089-77-9

Upstream product

• 54089-75-7 (S)-(+)-3-(4-Chlorophenyl)-3-phthalimidineacetic Acid 
• 108-90-7 chlorobenzene 
• 26859-66-5 1-(4-chlorophenyl)-3-ethoxy-1H-isoindole 
• 74113-24-9 [1-(4-Chloro-phenyl)-3-ethoxy-1H-isoindol-1-yl]-acetic acid methyl ester 

Downstream Products

• 55516-85-3 (αR,1S)-(-)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-88-6 (αS,1S)-(+)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-84-2 (αS,3S)-(+)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 
• 55516-81-9 (αR,3S)-(+)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 

Relevant academic research and scientific papers

Stereoselective Synthesis and Relative and Absolute Configuration of α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol

When 1-(4-chlorophenyl)-1-(4'-chlorophenacyl)-3-ethoxy-1H-isoindole (2) was reduced in the presence of diborane (αRS,1RS)-α,1-bis(4-chlorophenyl)isoindoline-1-ethanol (3a) was isolated in 88percent yield.The crude reduction product also contained the seco