54107-99-2

Usage

Uses

Used in Pharmaceutical Industry:
Dimethyl quinoxaline-2,3-dicarboxylate is used as an antimicrobial and antifungal agent for its ability to combat various microorganisms, which can be beneficial in the development of new drugs and treatments.
Used in Agricultural Industry:
In agriculture, dimethyl quinoxaline-2,3-dicarboxylate is utilized as a biocidal agent to protect crops from microbial and fungal infections, thereby enhancing crop yield and quality.
Used as a Dye Intermediate:
Dimethyl quinoxaline-2,3-dicarboxylate serves as a dye intermediate in the chemical industry, contributing to the synthesis of various dyes with specific color properties.
Used in Organic Synthesis:
As a building block in organic synthesis, dimethyl quinoxaline-2,3-dicarboxylate is employed in the creation of other complex organic compounds, expanding its utility in chemical research and development.
Used in Corrosion Inhibition:
Dimethyl quinoxaline-2,3-dicarboxylate has been studied for its potential as a corrosion inhibitor in industrial processes, where it can help protect materials from degradation and extend their service life.

Upstream product

• 67-56-1 methanol 
• 6924-99-8 Quinoxaline-2,3-dicarboxylic acid 
• 133-47-1 dimethyl dihydroxyfumarate 
• 273-13-2 benzo[1,2,5]thiadiazole 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 273-15-4 piazselenole 
• 95-54-5 1,2-diamino-benzene 
• 221171-89-7 dimethyl 2-bromo-2H-azirine-2,3-dicarboxylate 
• 146651-75-4 tert–butyl (2–aminophenyl)carbamate 
• 62-53-3 aniline 
• 4916-29-4 dimethyl 2-(phenyl-amino)-2-butendioate 

Downstream Products

• 6924-99-8 Quinoxaline-2,3-dicarboxylic acid 
• 5660-34-4 quinoxaline-2,3-dicarboxylic acid anhydride 
• 37648-53-6 2-(p-tolyl)-1H-pyrrolo[3,4-b]quinoxaline-1,3(2H)-dione 
• 85414-82-0 2-aminoquinoxaline-3-carboxylic acid 
• 54107-98-1 3-benzenesulfonyloxyalloxazine 
• 54108-08-6 3-hydroxy-1H-benzo[g]pteridine-2,4-dione 

Relevant academic research and scientific papers

Isobutyl Nitrite-Mediated Synthesis of Quinoxalines through Double C?H Bond Amination of N-Aryl Enamines

An efficient and metal-free double C?H bond amination of N-aryl enamines using isobutyl nitrite (IBN) has been developed. This method enables the preparation of functionalized quinoxalines in good to excellent yields and tolerates a variety of N-aryl enamines with diverse functional substituents. Mechanistic studies revealed the presence of a key β-imino oxime ester intermediate. A quinoxaline derivative could be prepared from β-carbonyl ester in one-pot sequence on a gram scale. Finally, two important quinoxaline scaffolds were easily prepared in moderate yields over two steps. (Figure presented.).

Hypervalent iodine(III)-promoted: N -incorporation into N -aryl vinylogous carbamates to quinoxaline diesters: Access to 1,4,5,8-tetraazaphenanthrene

A novel oxidative N-incorporation strategy for synthesis of quinoxaline diesters under metal-free conditions is described for the first time. The mild reaction conditions allow for this transformation via the formation of two C(sp2)-N bonds utilizing cheaply available NaN3 as the N-atom source. N-Aryl vinylogous carbamates in this study undergo azidation at enamino C(sp2)-H selectively. The robustness of this strategy is further demonstrated by the synthesis of a valuable 1,4,5,8-tetraazaphenanthrene derivative using a mild and convenient approach.

Efficient synthesis method of quinoxalinone derivatives

The invention discloses a synthesis method of quinoxalinone derivatives. According to the new route, enamine compounds obtained by synthesizing ordinary arylamine, keto ester, 3-oxo-nitrile or 1,3-dicarbonyl are used as the raw material, and 2,3-disubstit

Hypervalent iodine(iii)-induced oxidative [4+2] annulation of o-phenylenediamines and electron-deficient alkynes: Direct synthesis of quinoxalines from alkyne substrates under metal-free conditions

Hypervalent iodine(iii)-induced oxidative [4+2] annulation of o-phenylenediamines and electron-deficient alkynes under metal-free conditions has been developed. The reaction allows for direct access to quinoxalines bearing two electron-withdrawing groups in an efficient manner.

Reactivity of 2-Halo-2H-azirines. 1. Reactions with Nucleophiles

Nucleophilic substitution reactions of 2-halo-2H-azirines 1a, 1b, 1d, and 1e with potassium phthalimide and aniline allowed the preparation of new substituted 2H-azirines 2-5. The reactions of 2-bromo-2H-azirine 1a with methylamine led to the synthesis of

Novel Benzyne Additions to the 1,2,5-Thiadiazole and 1,2,5-Selenadiazole Ring Systems

Novel modes of benzyne addition to 3,4-dimethyl-1,2,5-thiadiazole and 3,4-dimethyl-1,2,5-selenadiazole afford methyl derivatives of three heterocyclic systems: quinoxaline, 1,2-benzisothiazole, and 1,3-benzoselenazole respectively.