54108-51-9

Usage

Uses

Used in Pharmaceutical Industry:
1-Methanesulfonyl-naphthalene is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Methanesulfonyl-naphthalene is utilized as a building block for the production of agrochemicals, playing a crucial role in the development of effective pesticides and other agricultural chemicals.
Used in Dye Industry:
1-Methanesulfonyl-naphthalene is employed as a precursor in the synthesis of dyes, contributing to the creation of a wide range of colorants used in various industries.
Used in Organic Synthesis:
1-Methanesulfonyl-naphthalene is used as a reagent in sulfonylation reactions for organic synthesis, providing mild reactivity and high selectivity, which is essential for the production of various organic compounds.

InChI:InChI=1/C11H10O2S/c1-14(12,13)11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3

Upstream product

• 77924-16-4 5-(8-Methanesulfonyl-naphthalen-2-yloxy)-1-phenyl-1H-tetrazole 
• 91-20-3 naphthalene 
• 75-75-2 methanesulfonic acid 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 18506-76-8 1-(benzylsulfonyl)naphthalene 
• 62062-39-9 1-naphthalen-1-yl-piperidine 

Relevant academic research and scientific papers

Polystyrene supported Al(OTf)3: A stable, efficient, selective, and reusable catalyst for sulfonylation of arenes with sulfonic acids

Cross-linked polystyrene supported aluminium triflate (Ps-Al(OTf) 3) was found to be an efficient and chemoselective heterogeneous Lewis acid catalyst for the direct conversion of arenes to sulfones using sulfonic acids as sulfonylating agents. The solid acid catalyst is stable (as a bench top catalyst) and can be easily recovered and reused without appreciable change in its efficiency.

Study of regioselective methanesulfonylation of simple aromatics with methanesulfonic anhydride in the presence of zeolite catalysts

Regioselective methanesulfonylation of simple aromatics using methanesulfonic anhydride can be achieved over zeolite catalysts. For example, methanesulfonylation of toluene over various cation-exchanged zeolite β catalysts affords higher para-selectivity in the synthesis of methyl tolyl sulfone than standard Friedel Crafts methanesulfonylation utilising aluminium chloride.

METAL-ASSISTED REACTIONS-13. RAPID, SELECTIVE REDUCTIVE CLEAVAGE OF PHENOLIC HYDROXYL GROUPS BY CATALYTIC TRANSFER METHODS

Previous work has shown that, after converting phenols into suitable phenolic ethers, the aromatic C-O bond of the original phenol can be reductively cleaved heterogeneously to give a C-H bond through the use of molecular hydrogen or hydrogen donors together with a transition metal catalyst.The present work provides a method for selectively replacing a phenolic OH group by H in just a few minutes, compared with the 2 to 4 hr required previously using a hydrogen donor and the several hours under pressure required for molecular hydrogen.Various kinds of groups are suitable for preparing the required phenolic ethers from phenols, but the best ones are strongly electronwithdrawing heteroaromatic entities.Solvent appears to play an important role in this heterogeneous reaction, the mechanism of which is discussed.