5416-45-5

Basic information

• Product Name: Diphenylcarbamic acid phenyl ester
• Synonyms: Diphenylcarbamic acid phenyl ester
• CAS NO: 5416-45-5
• Molecular Formula: C₁₉H₁₅NO₂
• Molecular Weight: 289.3279
• Mol File: 5416-45-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 413.1°Cat760mmHg
• Flash Point: 203.7°C
• Appearance: /
• Density: 1.207g/cm³
• Vapor Pressure: 4.91E-07mmHg at 25°C
• Refractive Index: 1.642
• CAS DataBase Reference: Diphenylcarbamic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Diphenylcarbamic acid phenyl ester(5416-45-5)
• EPA Substance Registry System: Diphenylcarbamic acid phenyl ester(5416-45-5)

Safety Data

• Hazardous Substances Data: 5416-45-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H15NO2/c21-19(22-18-14-8-3-9-15-18)20(16-10-4-1-5-11-16)17-12-6-2-7-13-17/h1-15H

Upstream product

• 122-39-4 diphenylamine 
• 139-02-6 sodium phenoxide 
• 83-01-2 diphenylcarbamic chloride 
• 108-95-2 phenol 
• 100-67-4 potassium phenolate 
• 64-17-5 ethanol 
• 110-86-1 pyridine 
• 56500-07-3 phenyl-carbonimidic acid diphenyl ester 

Downstream Products

• 97071-08-4 Diphenyl-carbamic acid phenyl ester; compound with GENERIC INORGANIC NEUTRAL COMPONENT 

Relevant articles and documents

A novel and efficient strategy for the synthesis of various carbamates using carbamoyl chlorides under solvent-free and grinding conditions using microwave irradiation

We present an efficient, fast and simple strategy of generating the intermediate carbamoyl chlorides from secondary amines using stoichiometric amounts of bis(trichloromethyl)carbonate (BTC) in solution and solvent-free conditions with excellent yields. The results obtained showed the yield increasing on whether a base was used. Finally, an efficient and rapid synthesis of variety carbamate derivatives was developed by the reaction with a high variety of different alcohols, phenols, diols and this intermediate at room temperature with grinding and in solvent-free conditions under microwave irradiation. The presence of various safe bases is shown to be effective in reducing the reaction times, increasing the yields and easing purification. The present method does not involve any hazardous phosgene.

Composition and method for inhibiting platelet aggregation

This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis. The method comprises administering to a subject a pharmaceutical composition comprising a therapeutic effective amount of P2Y12 receptor antagonist compound, wherein said amount is effective to bind the P2Y12 receptors on platelets and inhibit ADP-induced platelet aggregation. The P2Y12 receptor antagonist compounds useful for this invention include mononucleoside polyphosphates and dinucleoside polyphosphates of general Formula I, or salts thereof. The present invention also provides novel compositions comprising mononucleoside polyphosphates and dinucleoside polyphosphates according to Formula Ia and Ib.