54176-27-1Relevant articles and documents
Dynamic dye emission ON/OFF systems by a furan moiety exchange protocol
Gong, Junbo,Wang, Ying,Zhang, Qi,Zhang, Xin
, (2021)
Four triphenylamine-based dyes were synthesized by fluorescence turn on reactions. Optical behaviours, molecular arrangements, donor-to-acceptor charge transfer and dipole interactions of these functional dyes were investigated by UV–vis absorption and fluorescence spectroscopy, single-crystal X-ray diffraction and electrochemical cyclic voltammetry. The irreversible isomerization of itaconimide dye leads to an irreversible emission switch ON to OFF. Reversible Diels-Alder reaction of these dyes lead to a reversible emission switch OFF/ON. These luminescent dyes demonstrate dynamic dye molecular features by furan moiety exchanges to form energy-minimized and optimized dye molecular structures. In the dynamic molecular system, α-position furan-substituted dye was converted into more stable β-position furan-substituted dye according to 1H NMR spectroscopic monitoring.
PROGNOSTIC BIOMARKERS FOR TTK INHIBITOR CHEMOTHERAPY
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Page/Page column 50, (2016/10/31)
The present invention provides a method for identifying a tumor - in a human individual or in an animal - that is susceptible to treatment with a TTK inhibitor, said method comprising: a] providing a sample of a tumor; b] determining the presence of a mutated CTNNB1 gene in said tumor sample, wherein said mutation is located in exon 3 of CTNNB1 and whereby the presence of a mutated CTNNB1 gene indicates that the tumor is susceptible to treatment with a TTK inhibitor. In an alternative aspect, step b] of the above defined method is replaced by the step of determining the presence of a mutated CTNNB1 protein in said tumor sample, wherein said mutation is located in exon 3 of CTNNB1 and whereby the presence of a mutated CTNNB1 protein indicates that the tumor is susceptible to treatment with a TTK inhibitor. In a further alternative, step b] comprises determining an altered expression of a CTNNB1 regulated gene, whereby an altered expression of a CTNNB1 regulated gene indicates that the tumor is susceptible to treatment with a TTK inhibitor.
MONOMERS AND POLYMERS DERIVED FROM NATURAL PHENOLS
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Paragraph 0120-0121, (2016/02/15)
Monomers, polymers and copolymers are provided that incorporate at least one naturally occurring phenolic compound, such as a plant phenol, as well as methods for producing the monomers and polymers. Plant phenols possessing a reactive group in addition t
