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N-methyl-1-(naphthalen-1-yl)-N-(naphthalen-1-ylmethyl)methanamine is a complex organic compound with the molecular formula C21H21N. It is a derivative of methanamine, featuring two naphthalene rings and a methyl group. The compound is characterized by its unique structure, where one naphthalene ring is directly attached to the nitrogen atom, while the other is connected through a methylene bridge. This arrangement endows the molecule with specific chemical properties and potential applications in various fields, such as pharmaceuticals, materials science, and chemical research. Due to its complex structure, the compound may exhibit unique reactivity and stability, making it a subject of interest for further investigation and potential development.

5418-22-4

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5418-22-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5418-22-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,1 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5418-22:
(6*5)+(5*4)+(4*1)+(3*8)+(2*2)+(1*2)=84
84 % 10 = 4
So 5418-22-4 is a valid CAS Registry Number.

5418-22-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-1-naphthalen-1-yl-N-(naphthalen-1-ylmethyl)methanamine

1.2 Other means of identification

Product number -
Other names methyl-bis-naphthalen-1-ylmethyl-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5418-22-4 SDS

5418-22-4Downstream Products

5418-22-4Relevant academic research and scientific papers

N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-yl methyl)methylamines related to naftifine. Synthesis and antifungal activity

Di Santo, Roberto,Costi, Roberta,Artico, Marino,Massa, Silvio,Musiu, Chiara,Milia, Carlo,Putzolu, Monica,La Colla, Paolo

, p. 98 - 108 (2007/10/03)

Various pyrrole analogues of the antifungal drug naftifine were prepared starting from cinnamates via the tosylmethylisocyanide (TosMIC) reaction. After alkylation and hydrolysis, the intermediate arylpyrrole esters afforded 1-alkyl-4-aryl-1H-pyrrole-3-carboxylic acids, which were condensed with N-(1-naphthylmethyl)methylamine in the presence of EDCI and triethylamine. The related amides were then reduced with lithium aluminum hydride to the required N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-ylmethyl)methylamines. The new compounds were evaluated for antifungal activity in comparison with naftifine and other imidazole drugs used in the clinic. Derivative 7c was active against Candida parapsilosis and compound 51 against Candida albicans. Weak activity against dermatophytes was shown by a number of derivatives. Moreover, compounds 4g, 4j, 4k and 4p were found active against Staphylococcus aureus with potencies comparable to that of streptomycin.

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