54197-64-7 Usage
Description
6-Methoxy-3,4-dihydro-1H-quinolin-2-one, also known as 2-methoxy-3,4-dihydroquinolin-1(2H)-one, is a white solid chemical compound with the molecular formula C10H11NO2. It belongs to the class of organic compounds known as 3,4-dihydro-2H-1-benzopyran-2-ones and is soluble in water. As a derivative of quinolin-2(1H)-one, it is commonly used in the synthesis of pharmaceuticals and fine chemicals due to its potential pharmacological properties.
Uses
Used in Pharmaceutical Synthesis:
6-Methoxy-3,4-dihydro-1H-quinolin-2-one is used as an intermediate in the synthesis of pharmaceuticals and fine chemicals for its potential pharmacological properties.
Used in Antimicrobial Applications:
6-Methoxy-3,4-dihydro-1H-quinolin-2-one is used as an antimicrobial agent, exhibiting activity against various microorganisms, which makes it a valuable compound in the development of new antimicrobial drugs.
Used in Anti-inflammatory Applications:
6-Methoxy-3,4-dihydro-1H-quinolin-2-one is used as an anti-inflammatory agent, demonstrating the ability to reduce inflammation, which can be beneficial in the treatment of various inflammatory conditions.
Used in Diabetic Complications Management:
6-Methoxy-3,4-dihydro-1H-quinolin-2-one is studied for its potential as an inhibitor of aldose reductase, an enzyme involved in diabetic complications. Its use as an aldose reductase inhibitor could help in managing and treating complications associated with diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 54197-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,9 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 54197-64:
(7*5)+(6*4)+(5*1)+(4*9)+(3*7)+(2*6)+(1*4)=137
137 % 10 = 7
So 54197-64-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO2/c1-13-8-3-4-9-7(6-8)2-5-10(12)11-9/h3-4,6H,2,5H2,1H3,(H,11,12)
54197-64-7Relevant articles and documents
Room Temperature Benzofused Lactam Synthesis Enabled by Cobalt(III)-Catalyzed C(sp2)?H Amidation
Tian, Xun,Li, Xin,Duan, Shengzu,Du, Ya,Liu, Tongqi,Fang, Yongsheng,Chen, Wen,Zhang, Hongbin,Li, Minyan,Yang, Xiaodong
, p. 1050 - 1058 (2020/12/18)
Benzofused lactams, especially indolin-2-one and dihydroquinolin-2-one are popular structural motives in durgs and natural products. Herein, we developed a room temperature and robust synthesis of benzofused lactams through cobalt(III)-catalyzed C(sp
Synthesis of Lactams via Ir-Catalyzed C-H Amidation Involving Ir-Nitrene Intermediates
Li, Xiaoxun,Liu, Jitian,Tang, Weiping,Wang, Shuojin,Ye, Wenjing,Zheng, Junrong
, (2020/03/19)
x-membered lactams were synthesized via either an amidation of sp3 C-H bonds or an electrophilic substitution of arenes via Ir-nitrene intermediates. With the employment of a readily available iridium catalyst in dichloromethane or hexafluoro-2-propanol, a wide range of lactams were synthesized in good to excellent yields with high selectivity.
Revisiting Arene C(sp2)?H Amidation by Intramolecular Transfer of Iridium Nitrenoids: Evidence for a Spirocyclization Pathway
Hwang, Yeongyu,Park, Yoonsu,Kim, Yeong Bum,Kim, Dongwook,Chang, Sukbok
, p. 13565 - 13569 (2018/09/25)
Two mechanistic pathways, that is, electrocyclization and electrophilic aromatic substitution, are operative in most intramolecular C?H amination reactions proceeding by metal nitrenoid catalysis. Reported here is an alternative mechanistic scaffold leading to benzofused δ-lactams selectively. Integrated experimental and computational analysis revealed that the reaction proceeds by a key spirocyclization step followed by a skeletal rearrangement. Based on this mechanistic insight, a new synthetic route to spirolactams has been developed.
