5421-45-4

Usage

Uses

Used in Organic Synthesis:
(2-methylphenyl) 4-nitrobenzoate is used as a building block in organic synthesis for the preparation of various organic compounds.
Used in Pharmaceutical Industry:
(2-methylphenyl) 4-nitrobenzoate is used as a chemical intermediate in the development of pharmaceutical products.
Used in Agrochemical Industry:
(2-methylphenyl) 4-nitrobenzoate is used in the agrochemical industry for the synthesis of various agrochemical products.
Used in Dyes and Pigments Production:
(2-methylphenyl) 4-nitrobenzoate is used in the production of dyes and pigments due to its chemical properties.
Used in Medicinal Chemistry Research:
(2-methylphenyl) 4-nitrobenzoate is used as a subject of interest in medicinal chemistry research due to its potential biological activity and pharmacological applications.

InChI:InChI=1/C14H11NO4/c1-10-4-2-3-5-13(10)19-14(16)11-6-8-12(9-7-11)15(17)18/h2-9H,1H3

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 95-48-7 ortho-cresol 
• 62-23-7 4-nitro-benzoic acid 

Downstream Products

• 80645-51-8 p-nitrobenzoate de bromomethyl-2 phenyle 
• 80645-55-2 bromure de p-nitrobenzoyloxy-2 benzyltriphenylphosphonium 
• 787-64-4 2-(4-nitrophenyl)-1-benzofurane 

Relevant academic research and scientific papers

Unexpected migration of a benzoyl group in the intramolecular Wittig reaction of o-acyloxybenzylidenephosphoranes with benzoyl chlorides: One-pot synthesis of isomeric 3-benzoyl-2-phenylbenzofurans

The reaction of o-acyloxybenzylidenetriphenylphosphoranes with substituted benzoyl chlorides in an aprotic solvent led, together with the expected 2-phenylbenzofuran, to isomeric 3-benzoyl-2-phenylbenzofuran derivatives. This result formally corresponds to intramolecular migration of the benzoyl group from the ortho oxygen atom to the ylide carbanion via cyclization and ring opening of the starting o-acyloxybenzylidenetriphenylphosphoranes.

A novel photochemical Wittig reaction for the synthesis of 2-aryl/alkylbenzofurans

The synthesis of 2-aryl/alkylbenzofurans has been achieved in high yields under photochemical conditions from readily accessible and suitably substituted phosphonium bromides by an intramolecular photochemical Wittig reaction onto aryloxycarbonyl groups.

5,5′-Dimethyl-3,3′-azoisoxazole as a new heterogeneous azo reagent for esterification of phenols and selective esterification of benzylic alcohols under Mitsunobu conditions

5,5′-Dimethyl-3,3′-azoisoxazole is used as a new efficient heterogeneous azo reagent for the highly selective esterification of primary and secondary benzylic alcohols and phenols with aliphatic and aromatic carboxylic acids via Mitsunobu protocols. The reaction is highly selective for primary benzylic alcohols versus secondary ones, aliphatic alcohols and also phenols. The isoxazole hydrazine byproduct can be simply isolated by filtration and recycled to its azoisoxazole by oxidation.