54231-46-8

Upstream product

• 54231-35-5 3-fuoro-2-nitropyridine 
• 62-53-3 aniline 
• 54231-32-2 3-chloro-2-nitropyridine 

Downstream Products

• 68765-56-0 3-N-phenylpyridine-2,3-diamine 
• 1393177-41-7 [(S)-1-(3-phenylaminopyridin-2-ylcarbamoyl)ethyl]carbamic acid tert-butyl ester 
• 1393177-42-8 [(S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethyl]carbamic acid tert-butyl ester 
• 1393177-43-9 (S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethylamine 
• 1393181-40-2 [1-(1-Phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-ethyl]-(9H-purin-6-yl)-amine 
• 1404085-69-3 (S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)propan-1-amine 
• 1404085-68-2 (S)-tert-butyl 1-oxo-1-(3-(phenylamino)pyridin-2-ylamino)butan-2-ylcarbamate 
• 1404086-78-7 (S)-N-(1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)propyl)-9H-purin-6-amine 
• 1404085-63-7 (S)-N-(1-(1-Phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethyl)acetamide 
• 1404085-62-6 2-(chloromethyl)-1-phenyl-1H-imidazo[4,5-b]pyridine 
• 1404086-74-3 6-((1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)methylthio)-9H-purine 
• 1404086-73-2 9-((1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)methyl)-9H-purin-6-amine 

Relevant academic research and scientific papers

Imidazopyridine derivatives as PI3K inhibitors

New imidazopyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)

IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS

New imidazopyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Nitro, amino and aroylamino-N-phenylpyridinamines in a process for preparing pyrido[1,4]benzodiazepines

Nitro, amino and aroylamino-N-phenylpyridinamines as chemical intermediates and/or having antidepressant activity having the formula STR1 wherein R3 is nitro, amino or aroylamino, and Q is hydrogen, --NR1 R2 or halogen are disclosed in a process for preparing pyrido[1,4]benzodiazepines.