54231-46-8

Basic information

• Product Name: (2-nitro-pyridin-3-yl)-phenyl-amine
• Synonyms: (2-nitro-pyridin-3-yl)-phenyl-amine
• CAS NO: 54231-46-8
• Molecular Weight: 215.211
• Mol File: 54231-46-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-nitro-pyridin-3-yl)-phenyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-nitro-pyridin-3-yl)-phenyl-amine(54231-46-8)
• EPA Substance Registry System: (2-nitro-pyridin-3-yl)-phenyl-amine(54231-46-8)

Safety Data

• Hazardous Substances Data: 54231-46-8(Hazardous Substances Data)

Upstream product

• 54231-32-2 3-chloro-2-nitropyridine 
• 62-53-3 aniline 
• 54231-35-5 3-fuoro-2-nitropyridine 

Downstream Products

• 68765-56-0 3-N-phenylpyridine-2,3-diamine 
• 1393177-41-7 [(S)-1-(3-phenylaminopyridin-2-ylcarbamoyl)ethyl]carbamic acid tert-butyl ester 
• 1393177-42-8 [(S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethyl]carbamic acid tert-butyl ester 
• 1393177-43-9 (S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethylamine 
• 1393181-40-2 [1-(1-Phenyl-1H-imidazo[4,5-b]pyridin-2-yl)-ethyl]-(9H-purin-6-yl)-amine 
• 1404086-73-2 9-((1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)methyl)-9H-purin-6-amine 
• 1404086-74-3 6-((1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)methylthio)-9H-purine 
• 1404085-62-6 2-(chloromethyl)-1-phenyl-1H-imidazo[4,5-b]pyridine 
• 1404085-63-7 (S)-N-(1-(1-Phenyl-1H-imidazo[4,5-b]pyridin-2-yl)ethyl)acetamide 
• 1404085-69-3 (S)-1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)propan-1-amine 
• 1404085-68-2 (S)-tert-butyl 1-oxo-1-(3-(phenylamino)pyridin-2-ylamino)butan-2-ylcarbamate 
• 1404086-78-7 (S)-N-(1-(1-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)propyl)-9H-purin-6-amine 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS

New imidazopyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).