54246-57-0

Basic information

• Product Name: 5-methoxy-1-phenyl-1H-tetrazole
• Synonyms: 5-methoxy-1-phenyl-1H-tetrazole
• CAS NO: 54246-57-0
• Molecular Weight: 176.178
• Mol File: 54246-57-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-methoxy-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-1-phenyl-1H-tetrazole(54246-57-0)
• EPA Substance Registry System: 5-methoxy-1-phenyl-1H-tetrazole(54246-57-0)

Safety Data

• Hazardous Substances Data: 54246-57-0(Hazardous Substances Data)

Upstream product

• 1154397-00-8 1-phenyl-5-(vinylsulfonyl)-1H-tetrazole 
• 124-41-4 sodium methylate 
• 86-93-1 1-phenyl-1H-tetrazole-5-thiol 
• 1455-92-1 5-methylsulfanyl-1-phenyl-1H-tetrazole 
• 67-56-1 methanol 
• 1483-25-6 1-phenyl-5-phenoxy-1H-tetrazole 
• 3206-44-8 5-methanesulfonyl-1-phenyl-1H-tetrazole 

Relevant articles and documents

Expanding the Potential of Heteroaryl Vinyl Sulfones

The easily available vinyl sulfone 3 showed great potential for new applications in several fields such as organic synthesis and bioconjugate formation. This was demonstrated by performing a systematic assessment of its reactivity in Michael, radical, and cycloaddition reactions. Heteroaryl vinyl sulfone 3 presented excellent output in terms of reactivity and selectivity, proving superior to phenyl vinyl sulfone 1 and with clear advantages over bis-sulfone 2. This behavior might be due to the conformational and orbital control exerted by the tetrazole unit according to DFT calculations. Moreover, some alternative transformations to the Julia-Kocienski olefination on the obtained products are also described.

Tetrazoles. XXXI. Phase-Transfer Reactions of 1-Substituted Tetrazole-5-thiones and Their Derivatives

Alkylation of 1-substituted tetrazole-5-thiones under conditions of phase-transfer catalysis in the two-phase system liquid-liquid proceeds regioselectively at the sulfur atom, regardless of the alkylating agent and phase-transfer catalyst. Phase-transfer oxidation of the 5-alkylthiotetrazoles thus obtained by potassium permanganate is a convenient method for preparation of 5-alkylsulfonyltetrazoles which can be used to synthesize functionally substituted tetrazoles.

Simple Method of Preparation 5-Alkyl(aryl)oxy-1-Phenyltetrazoles

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