5427-22-5

Upstream product

• 857401-38-8 9-ethyl-6-dimethylamino-2-methylsulfanyl-7,9-dihydro-purine-8-thione 
• 90085-36-2 6-dimethylamino-2-methylsulfanyl-7,9-dihydro-purine-8-thione 
• 98841-02-2 (2,8-bis-methylsulfanyl-7⁽⁹⁾H-purin-6-yl)-dimethyl-amine 
• 857991-11-8 N⁶-ethyl-N⁴,N⁴-dimethyl-2-methylsulfanyl-5-nitroso-pyrimidine-4,6-diyldiamine 
• 98140-03-5 6-chloro-N⁴-ethylpyrimidine-4,5-diamine 
• 87-42-3 6-chloropurine 
• 75-03-6 ethyl iodide 
• 938-55-6 6-Dimethylaminopurine 
• 857400-79-4 (9-ethyl-2,8-bis-methylsulfanyl-9H-purin-6-yl)-dimethyl-amine 
• 5462-86-2 6-chloro-9-ethyl-9H-purine 
• 124-40-3 dimethyl amine 

Relevant academic research and scientific papers

Purine Derivatives as Competitive Inhibitors of Human Erythrocyte Membrane Phosphatidylinositol 4-Kinase

The possibility of deriving a potent, cell-penetrating inhibitor of human erythrocyte PI 4-kinase, competitive with respect to ATP, has been investigated in a series of purine derivatives and analogues.The purine nucleus is not essential for binding to th

SYNTHESES OF N,N,3- AND N,N,9-TRIALKYLADENINES BY ALKYLATION OF N,N-DIYLKYLADENINES

Alkylation of N,B,N-dimethyl- (Ia) and N,N-diethyladenine (Ib) with methyl iodide, ethyl iodide, and benzyl bromide in N,N-dimethylacetamide in the presence of potassium carbonate gave the corresponding N,N,9-trialkyladenines (II) in 54-74percent yields, as well as minor amounts of N,N,3-trialkyladenines (III).The alkylation of I without base gave the latter compounds (III) in 76-90percent yields.Keywords - N,N,3-tryalkyladenines: N,N,9-trialkyladenines; regioselective N-alykaltion; N,N-dialkyladenines; isomer ratio.