54288-07-2Relevant academic research and scientific papers
Generation of a silylethylene-titanium alkoxide complex. A versatile reagent for silylethylation and silylethylidenation of unsaturated compounds
Mizojiri, Ryo,Urabe, Hirokazu,Sato, Fumie
, p. 6217 - 6222 (2000)
(Trimethylsilyl)ethylene-titanium alkoxide complex (1) was generated from trimethyl(vinyl)silane, Ti(O-i-Pr)4, and i-PrMgCl as a preformed alkene-titanium complex and reacted with several unsaturated compounds such as aldehyde, imine, other vin
The S(H)i reaction at silicon - A new entry into cyclic alkoxysilanes
Studer, Armido,Steen, Hanno
, p. 759 - 773 (2007/10/03)
A new mild radical method for the preparation of cyclic five-membered alkoxysilanes is reported. This method comprises an intramolecular homolytic substitution reaction at silicon (S(H)i). Various leaving groups (SiMe3, GeMe3, SnMe3) were tested in the homolytic substitution reaction. We found that high yields were only obtained for silanes bearing a trimethyl-stannyl functionality as leaving group in the S(H)i reaction. Rate constants for the cyclization reaction were estimated by conducting standard competition experiments. Based on the kinetic data, more elaborate reaction sequences such as radical addition reactions with a subsequent S(H)i step were carried out. Stereoselective cyclization reactions were also investigated. Excellent 1,2 diastereoselectivities were observed. The products of the S(H)i reaction, cyclic alkoxysilanes, can easily be converted to the corresponding diol derivatives by Tamao-Fleming oxidation as demonstrated for several examples.
lithium: A New Reagent for Carbonyl Reductive Vinylation
Wilson, Stephen R.,Shedrinsky, Alexander
, p. 1983 - 1984 (2007/10/02)
The direct transformation of a carbonyl compound into a vinyl compound (i.e., cyclohexanone vinylcyclohexane) is now possible with use of the new reagent described in this paper: lithium, followed by protodesilylation.
