5429-07-2 Usage
General Description
2-[(7-Chloro-4-quinolinyl)sulfanyl]acetic acid is a chemical compound from the group of organosulfur compounds, specifically a quinolinylsulfanyl acetic acid. The compound is composed of a 7-chloroquinoline ring attached to a sulfanyl group which in turn is bonded to an acetic acid moiety. The exact physical properties such as boiling point, melting point, toxicity, and the like may vary and are typically studied thoroughly. This chemical can be used in various industrial, pharmaceutical or chemical applications, subject to its properties and the regulatory approvals. However, its exact applications, stability, and safety profile have not been commonly reported in open literature.
Check Digit Verification of cas no
The CAS Registry Mumber 5429-07-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5429-07:
(6*5)+(5*4)+(4*2)+(3*9)+(2*0)+(1*7)=92
92 % 10 = 2
So 5429-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H8ClNO2S/c12-7-1-2-8-9(5-7)13-4-3-10(8)16-6-11(14)15/h1-5H,6H2,(H,14,15)
5429-07-2Relevant articles and documents
Synthesis and antimalarial activity of (S)-methyl-(7-chloroquinolin-4-ylthio)acetamidoalquilate derivatives
Colmenarez, Custodiana,Acosta, María,Rodríguez, Miguel,Charris, Jaime
, p. 161 - 166 (2020/01/09)
The synthesis of five new (S)-methyl-(7-chloroquinolin-4-ylthio)acetamidoalquilate derivatives is carried out under a modified version of the Steglich esterification reaction between different l-amino acid methyl esters and 2-(7-chloroquinolin-4-ylthio)acetic acid. Two of the compounds showed significant inhibition (>50%) of β-hematin formation. The two active structures were tested in vivo as potential antimalarials in mice infected with Plasmodium berghei ANKA, a chloroquine susceptible strain. Compounds 6b and 6e exhibited antimalarial activity comparable to that of chloroquine.
