5429-33-4Relevant academic research and scientific papers
A novel approach to biologically relevant oxazolo[5,4-d]pyrimidine-5,7-diones via readily available diazobarbituric acid derivatives
Gecht, Martha,Kantin, Grigory,Dar'in, Dmitry,Krasavin, Mikhail
, (2019)
An alternative route from 1,3-disubstituted barbituric acids to biologically relevant oxazolo[5,4-d]pyrimidine-5,7-diones was developed that features sulfonyl-azide-free (SAFE) diazo transfer and Rh2(esp)2-catalyzed cycloaddition of
5,5′-bipyridyl-2,4,6,2′,4′,6′-hexaone derivatives (hydurilic acids): Syntheses, mechanism of C-C-Bond formation and properties of the dimeric barbituric acid derivatives
Mueller, Christa E.,Roegler, Carolin,Hockemeyer, Joerg
scheme or table, p. 703 - 720 (2009/12/26)
A series of hydurilic acid derivatives (5,5′-bipyrimidinyl-2,4,6,2′,4′,6′-hexaones) including several new derivatives was synthesized from 5,6-diaminouracils. Mechanisms for their formation are proposed and discussed. Furthermore, a new method for the preparation of pyrimidine-2,4,5,6-tetraone-5-oxime derivatives (violuric acids) was found starting from 5-amino-6-nitrosouracils.
Ring closure reactions of azidouracils to oxazolo- and isoxazolopyrimidines [1]
Van Tinh, Dang,Stadlbauer, Wolfgang
, p. 1025 - 1030 (2007/10/03)
Thermolysis of 6-azidouracils 1 in the presence of polyphosphoric acid leads either to oxazolo[5,4-d]pyrimidine-5,7-diones 5 (by reaction with benzoic acid 2a) or to isoxazolo[3,4-d]pyrimidine-4,6-diones 7 (by reaction with aliphatic carboxylic acids 2b,c
