543-29-3

Usage

Uses

Used in the Perfume Industry:
ISOBUTYL NITRATE is used as a volatile alkyl nitrate to enhance the fragrance of perfumes, providing a pleasant and fruity scent that contributes to the overall aroma profile of the product.
Used in the Chemical Industry:
As a solvent, ISOBUTYL NITRATE is employed for various chemicals, facilitating their dissolution and enabling a wide range of chemical reactions and processes.
Used in the Automotive Industry:
ISOBUTYL NITRATE is utilized in automotive fuels, where it serves as an antiozonant to prevent the formation of harmful ozone compounds, thereby improving fuel quality and engine performance.
Used in the Medical Field:
ISOBUTYL NITRATE is used as a vasodilator for the treatment of angina pectoris, a condition characterized by chest pain due to insufficient blood flow to the heart. Its vasodilating properties help to widen blood vessels, improving blood flow and alleviating symptoms.
However, it is important to note that ISOBUTYL NITRATE is a highly flammable and potentially hazardous compound. Therefore, its use and handling must be conducted with appropriate safety precautions to minimize risks and ensure the well-being of individuals and the environment.

InChI:InChI=1/C4H9NO3/c1-4(2)3-8-5(6)7/h4H,3H2,1-2H3

Upstream product

• 19910-12-4 peroxyisovaleric acid 
• 940-49-8 benzyl iso-butyl ether 
• 7697-37-2 nitric acid 
• 590-86-3 isovaleraldehyde 
• 78-83-1 2-methyl-propan-1-ol 

Downstream Products

• 78-84-2 isobutyraldehyde 

Relevant academic research and scientific papers

Separation of Diastereomeric and Enantiomeric Alkyl Nitrates - Systematic Approach to Chiral Discrimination on Cyclodextrin LIPODEX-D

High-resolution gas chromatographic separation of all diastereomeric monomethyl-substituted cyclohexyl nitrates is shown on a nonpolar methylpolysiloxane stationary phase, and the first application of this procedure to the environmental diastereomeric analysis of alkyl nitrates is presented.Two characteristic signals in the achiral analysis of atmospheric samples could be assigned to the smallest alkyl nitrate containing two asymmetric carbon atoms, 3-methyl-2-pentyl nitrate.Retention indices in the temperature-programmed separation based on the n-alkanes were determined.The homologous series of 1-alkyl nitrates were found to be useful as ECD-visible n-alkanes.Enantiomeric separation of alkyl nitrates was achieved on heptakis(3-O-acetyl,-2,6-di-O-pentyl)-β-cyclodextrin (LIPODEX-D).The influence of the nitrooxy group and the alkyl chain length on the chiral discrimination on LIPODEX-D is discussed for 25 chiral alkyl nitrates.The absolute configurations of some alkyl nitrates were assigned by asymmetric synthesis of enantiomerically pure references.The complexity of the alkyl nitrate mixtures present in air samoles does not allow a direct chiral separation as the alkyl nitrates partly coelute on the LIPODEX-D column.Column coupling of LIPODEX-D with a polar achiral stationary phase like polyalkylenglocol (PAG) was successfully applied to solve this problem, and the chiral alkyl nitrates present in a typical air sample were separated.A systematic nomenclature for alkyl nitrates is introduced to handle the steadily growing number of branched and long-chain nitrates detected in environmental analysis. - Keywords: analytical methods; alkyl nitrates; chiral resolution; cyclodextrins; gas chromatography

Formation and Thermal Decomposition of Butyl-Substituted Peroxyacyl Nitrates: n-C4H9C(O)OONO2 and i-C4H9C(O)OONO2

The butyl-substituted peroxyacyl nitrates n-C4H9C(O)OONO2 and i-C4H9C(O)OONO2 have been synthesized in the liquid phase, prepared in-situ in the gas phase by sunlight irradiation of aldehyde-NO mixtures, measured by electron capture gas chromatography, and characterized in a number of gas-phase and liquid-phase tests. Gas-phase yields as a fraction of initial NO were 0.39 for the n-butyl isomer and 0.20 for the isobutyl isomer. The corresponding gas-phase aldehyde oxidation mechanisms are outlined. Thermal decomposition in the presence of excess NO yielded n-butanal and isobutanal as the major carbonyl products. Thermal decomposition rates at ambient temperature and atmospheric pressure are comparable to that of PAN , with k298 = 1.8E-4 s-1 for n-C4H9C(O)OONO2 and 2.4E-4 s-1 for i-C4H9C(O)OONO2. Emission data for precursor hydrocarbons indicate C4H9C(O)OONO2/PAN ambient concentration ratios of 0.19 in urban air. Atmospheric implications for the formation and removal of C4H9C(O)OONO2 are briefly discussed.

Convenient preparation of alkyl nitrates free of nitrites with potassium nitrate and boron trifluoride hydrate

Primary and secondary alkyl nitrates free of nitrites were conveniently prepared by treating the corresponding alcohols with potassium nitrate and boron trifluoride 1.25 hydrate. This procedure was also successful for the preparation of 1-adamantyl nitrate.