54311-64-7

Basic information

• Product Name: Benzeneacetic acid, a-chloro-a-phenyl-, methyl ester
• Synonyms: Methyl α-chlorodiphenylacetate;Chlor-diphenyl-essigsaeure-methylester;diphenyl-chloroacetic acid methyl ester;(α-methoxycarbonyl)diphenylmethyl chlorid;methyl chlorodiphenylacetate;chloro-diphenyl-acetic acid methyl ester;METHYL-2-CHLORO-2,2-DIPHENYLACETATE
• CAS NO: 54311-64-7
• Molecular Formula: C15H13ClO2
• Molecular Weight: 260.72
• Mol File: 54311-64-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-chloro-a-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-chloro-a-phenyl-, methyl ester(54311-64-7)
• EPA Substance Registry System: Benzeneacetic acid, a-chloro-a-phenyl-, methyl ester(54311-64-7)

Safety Data

• Hazardous Substances Data: 54311-64-7(Hazardous Substances Data)

Upstream product

• 76-89-1 methyl benzilate 
• 67-56-1 methanol 
• 119-61-9 benzophenone 
• 76-93-7 Benzilic acid 
• 134-81-6 benzil 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 2902-98-9 2-chloro-2,2-diphenylacetyl chloride 
• 186581-53-3 diazomethane 
• 7475-56-1 chloro(diphenyl)acetic acid 

Downstream Products

• 3469-00-9 methyl 2,2-diphenylacetate 
• 51552-62-6 methoxy-diphenyl-acetic acid methyl ester 
• 31469-19-9 diphenyl-2,2 methoxy-1 trimethylsiloxy-1 ethylene 
• 4695-04-9 5,5-diphenyl-thiazolidine-2,4-dione 
• 20348-27-0 2,2-diphenyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine 
• 76-89-1 methyl benzilate 
• 20348-22-5 2,2-diphenyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 

Relevant articles and documents

3-Quinuclidinyl-α-methoxydiphenylacetate: A multi-targeted ligand with antimuscarinic and antinicotinic effects designed for the treatment of anticholinesterase poisoning

Racemic 3-quinuclidinyl-α-methoxydiphenylacetate (MB266) was synthesised. Its activity at muscarinic acetylcholine receptors (mAChRs), and muscle and neuronal nicotinic acetylcholine receptors (nAChRs), was compared to that of atropine and racemic 3-quinu

Nucleophilic substitution in diphenylmethyl derivatives. I. Formolysis of diarylmethyl derivatives: an α-substituent effect

The reactions of formic acid with and without addition of sodium formate with diphenylmethanol (4) and chlorodiphenylmethane (3) were compared to those with hydroxydiphenylacetic (benzilic) acid (12a) and chlorodiphenylacetic acid (14a).Formic acid did not favour any SN1-type reaction on 4, but a strong catalysis by iodide ion was observed.Sodium formate rapidly performed the substitution of the chlorine in 3.A similar outcome was obtained with chloro acid 14a, but the rationalization of the results is different.Chloro acid 14a and its methyl ester 14b were prompt to react, but the equilibria were shiftet to α-formyloxy products 13 only by the addition of HCOONa.HCOOH was unable to perform any reduction on either 3 or 4 or 12a and 14a, a fact which was taken as evidence for concerted substitution mechanism on ion pairs or betaine 15.Mechanistic implications are drawn.

Studies on antidiabetic agents. III. 5-arylthiazolidine-2,4-diones as potent aldose reductase inhibitors

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