5434-30-0

Usage

Uses

Used in Chemical Reactions:
N1-(5-Amino-2-methylphenyl)acetamide is used as a reactive compound in various chemical reactions, particularly in laboratory settings. Its reactivity allows it to participate in a wide range of chemical processes, making it a valuable tool for researchers and chemists.
Used in Scientific Research:
Due to its unique molecular structure and reactivity, N1-(5-Amino-2-methylphenyl)acetamide is used as a research compound in the field of organic chemistry. It may be employed in studies aimed at understanding the properties and behavior of arylethylamines or in the development of new chemical reactions and processes.
Used in Pharmaceutical Development:
Although information on its industrial applications is limited, N1-(5-Amino-2-methylphenyl)acetamide may have potential uses in the pharmaceutical industry. Its reactivity and molecular structure could make it a candidate for the development of new drugs or as an intermediate in the synthesis of pharmaceutical compounds.
Used in Material Science:
N1-(5-Amino-2-methylphenyl)acetamide's reactivity and molecular structure may also make it a candidate for use in material science research. It could be employed in the development of new materials or in the modification of existing materials to improve their properties, such as conductivity, stability, or reactivity.

Upstream product

• 7732-18-5 water 
• 64-19-7 acetic acid 
• 99-55-8 2-methyl-5-nitroaniline 
• 2879-79-0 N-(2-methyl-5-nitrophenyl)acetamide 

Downstream Products

• 641615-67-0 4-methyl-3-{N-acetyl-N-[5-(pyridin-3-yl)-1,2,4-triazin-3-yl]amino}aniline 
• 1447794-64-0 N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl) acetamide 
• 1447794-56-0 N-[5-[[3-cyano-7-[[1-(2-hydroxyethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]acetamide 
• 1447794-55-9 N-(5-(3-cyano-7-(1-(2-hydroxyethyl)-1H-pyrazol-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide 
• 1374006-38-8 C₁₈H₁₉N₃O₄ 
• 1374006-34-4 C₁₈H₂₁N₃O₂ 
• 1374006-29-7 C₁₆H₁₅Cl₂N₃O₂ 
• 1374006-31-1 C₁₈H₁₅F₆N₃O₂ 
• 1374006-32-2 C₁₇H₁₅ClF₃N₃O₂ 
• 1374006-30-0 C₁₆H₁₅Cl₂N₃O₂ 
• 1374006-35-5 C₁₈H₁₉N₃O₃ 
• 1374006-28-6 C₁₆H₁₆ClN₃O₂ 
• 1374006-36-6 C₂₂H₂₁N₃O₃ 
• 1374006-37-7 C₁₇H₁₇N₃O₄ 

Relevant academic research and scientific papers

INHIBITORS OF NECROPTOSIS

The invention relates to novel heterocyclic compounds of Formula (I) which inhibit necroptosis and methods for their use. The compounds may be useful in the treatment of conditions associated with deregulated necroptosis.

3 -CYANO- 5 -ARYLAMINO-7 -CYCLOALKYLAMINOPYRROLO [1, 5 -A] PYRIMIDINE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS

The invention relates to chemical compounds of Formula (I): or a salt thereof. In some embodiments, the invention relates to inhibitors of CK2. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein and their use in the prevention and treatment of CK2-related conditions and diseases, e.g., cancer.

New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: Design, synthesis, and antiproliferative activity against melanoma cell line

A series of new diarylurea and diarylamide derivatives possessing acet(benz)amidophenyl scaffold was synthesized. Their in vitro antiproliferative activity was tested against A375P human melanoma cell line. Compounds 1c,d and 2c,d showed the highest potencies with IC50 values in sub-micromolar scale. In addition, compounds 1b,e,l and 2e,l were more potent than Sorafenib but with IC50 values in micromolar range. Moreover, compound 2c was equipotent to Vemurafenib, and 2d showed higher potency than Vemurafenib against A375P. Molar refractometry calculation and ADME profiling of the highest potent four derivatives 1c,d and 2c,d are also reported.

AMIDE DERIVATIVE

The present invention provides an amide derivative represented by the following general formula (1): wherein R1 represents a saturated cyclic amino group, R2 represents alkyl, halogen or haloalkyl, R3 represents hydrogen or halogen, Het 2 represents pyridyl or pyrimidinyl, and Het 1 represents a group of the formula [6], or a salt thereof, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention is useful as a BCR-ABL tyrosine kinase inhibitor.

Phthalocyanine reactive dyestuffs

Phthalocyanine reactive dyestuffs which, in the form of the free acid, have the formula (1) STR1 in which the variable radicals have the meaning given in the description, are prepared by condensation of the corresponding amines with cyanuric fluoride or cyanuric chloride in any desired order. The reactive dyestuffs according to the invention exhibit good wet and light fastness properties and are used for the dyeing and printing of cotton.