54340-91-9

Basic information

• Product Name: 2-Hydroxyheptanoic acid methyl ester
• Synonyms: 2-Hydroxyenanthic acid methyl ester;2-Hydroxyheptanoic acid methyl ester
• CAS NO: 54340-91-9
• Molecular Formula: C8H16O3
• Molecular Weight: 0
• Mol File: 54340-91-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Hydroxyheptanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxyheptanoic acid methyl ester(54340-91-9)
• EPA Substance Registry System: 2-Hydroxyheptanoic acid methyl ester(54340-91-9)

Safety Data

• Hazardous Substances Data: 54340-91-9(Hazardous Substances Data)

Upstream product

• 81114-75-2 1,1,1-tris(methylthio)-2-heptanol 
• 78935-59-8 E-methoxy-1 trimethylsiloxy-1 heptene-1 
• 145090-37-5 Acetic acid 1-methylsulfanylcarbonyl-hexyl ester 
• 67-56-1 methanol 
• 82722-11-0 1,1,1-Tris-ethylsulfanyl-heptan-2-ol 
• 186581-53-3 diazomethane 
• 52358-05-1 2-hydroxyheptanoic acid 
• 106-73-0 methyl heptanoate 
• 2863-47-0 1-methanesulfinyl-heptan-2-one 
• 106-70-7 methyl hexanoate 
• 66-25-1 hexanal 
• 86593-94-4 (E/Z)-1-methoxy-1-trimethylsilyloxy-1-heptene 
• 74-88-4 methyl iodide 

Downstream Products

• 56196-51-1 α-Acetoxy-heptansaeure-methylester 
• 54004-30-7 (E)-methyl hept-3-enoate 

Relevant articles and documents

Oxidation of Methyl Trimethylsilyl Ketene Acetals to α-Hydroxyesters with Urea Hydrogen Peroxide Catalyzed by Methyltrioxorhenium

In the presence of catalytic amounts of MTO, methyltrioxorhenium, methyl trimethylsilyl ketene acetals are oxidized with urea hydrogen peroxide to afford α-hydroxy and α-siloxy esters. On treatment with potassium fluoride, the α-hydroxy esters are obtained in high yields.

4-Hydroxynon-2-enal, a cytotoxic lipid peroxidation product, and its C5- analog 4-hydroxypent-2-enal: Enantioselective synthesis and stereoanalysis

A stereoselective synthesis of the lipid peroxidation products 4- hydroxypent-2-enal (1a) and 4-hydroxynon-2-enal (1b) in high optical purity is presented. The configuration of 1a and b was established by Ru(III)- catalyzed oxidative degradation and subsequent stereoanalysis of the resulting α-hydroxy acids. It was demonstrated that 1a is configuratively stable under physiological conditions.

Synthesis of S-Methyl 2-Hydrxyalkanethioates, 2-Hydroxyalkanoic Acids and Related Compounds via the Addition Reaction of Tris(methylthio)methanide Ion to Alkanals

In connection with the studies on biological activities on myrmicacin and related compounds, the synthetic method for 2-hydroxyalkanoic acids and the corresponding 1,2-diols was studied.The addition reaction of tris(methylthio)methyllithium to the aldehydes (propanal-dodecanal) gave the corresponding 1,1,-tris(methylthio)-2-alkanols 1a-j.Treatment of 1 with mercury(II) chloride-mercury(II) oxide in water-acetone afforded S-methyl 2-hydroxyalkanethioates 2a-j, and in methanol methyl 2-hydroxyalkanoates 3c-j were obtained.Reduction of the thioates 2 with lithium aluminium hydride gave 1,2-diols 4c-j and saponification produced the corresponding 2-hydroxyalkanoic acids 5c-j.