5435-24-5Relevant academic research and scientific papers
Nucleophilic Displacement at Benzhydryl Centers: Asymmetric Synthesis of 1,1-Diarylalkyl Derivatives
Bolshan, Yuri,Chen, Cheng-Yi,Chilenski, Jennifer R.,Gosselin, Francis,Mathre, David J.,O'Shea, Paul D.,Roy, Amelie,Tillyer, Richard D.
, p. 111 - 114 (2007/10/03)
(Equation presented) Activation of substituted 1,1-diarylmethanols as their corresponding toluenesulfonates and subsequent displacement with a range of carbon, nitrogen, oxygen, and sulfur nucleophiles proceeds in 81-96% yield. Enantiomerically enriched d
Synthesis and biological evaluation of tropane-like 1-{2-[bis(4-fluorophenyl)methoxy]ethyl})-4-(3-phenylpropyl)piperazine (GBR 12909) analogues
Zhang,Joseph,Bowen,Flippen-Anderson,Dersch,Rothman,Jacobson,Rice
, p. 3937 - 3945 (2007/10/03)
We have prepared azabicyclo[3.2.1] derivatives (C-3-substituted tropanes) that bind with high affinity to the dopamine transporter and inhibit dopamine reuptake. Within the series, 3-{(2-[bis-(4-fluorophenyl)methoxy] ethylidene}-8-methyl-8-azabicyclo[3.2.
