5437-99-0

Basic information

• Product Name: 8-nitroquinolin-6-ol
• Synonyms: 6-Hydroxy-8-nitroquinoline; 8-Nitro-6-quinolinol
• CAS NO: 5437-99-0
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.1555
• Mol File: 5437-99-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 392.3°C at 760 mmHg
• Flash Point: 191°C
• Density: 1.496g/cm³
• Vapor Pressure: 1.03E-06mmHg at 25°C
• Refractive Index: 1.728
• CAS DataBase Reference: 8-nitroquinolin-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-nitroquinolin-6-ol(5437-99-0)
• EPA Substance Registry System: 8-nitroquinolin-6-ol(5437-99-0)

Safety Data

• Hazardous Substances Data: 5437-99-0(Hazardous Substances Data)

Usage

General Description

8-nitroquinolin-6-ol, also known as 8-nitro-6-hydroxyquinoline, is a chemical compound with the molecular formula C9H6N2O3. It is a nitro-substituted quinolin-6-ol and is used as an intermediate in the production of pharmaceuticals, dyes, and other organic compounds. 8-nitroquinolin-6-ol has antibacterial and antifungal properties and has been the focus of research for its potential therapeutic applications. It is also used in the synthesis of fluorescent dyes and as a reagent in organic chemical reactions. Its structure and properties make it a valuable building block in organic synthesis and a versatile compound in the field of medicinal chemistry.

Upstream product

• 282547-59-5 6-ethoxy-8-nitro-quinoline 
• 610-81-1 4-hydroxy-2-nitroaniline 
• 107-02-8 acrolein 
• 616-86-4 2-nitro-4-ethoxyaniline 
• 885-81-4 N-(4-ethoxy-2-nitrophenyl)acetamide 
• 85-81-4 6-methoxy-8-nitroquinoline 

Downstream Products

• 282547-59-5 6-ethoxy-8-nitro-quinoline 

Relevant articles and documents

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COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER

This invention is in the field of medicinal chemistry. In particular, the invention relates to novel small molecule compounds having a quinolin-8-yl-nicotinamide structure which are useful in treating, ameliorating, or preventing various forms of cancer (e.g., pancreatic cancer).

ANTI-CANCER AGENT, METAL COMPLEX AND HETEROCYCLE COMPOUND

PROBLEM TO BE SOLVED: To provide an anti-cancer agent which is inexpensive because of no use of expensive noble metal, and has mechanisms of action different from conventional platinum formulations. SOLUTION: An anti-cancer agent contains as an active ingredient a metal complex represented by the general formula (1) in the figure. (In the formula, R1 represents a hydrogen atom, a C1-C6 alkoxy group or an alkyl group or the like; R2 represents a hydrogen atom, a C1-C6 alkoxy group or the like; R3 to R10 represent hydrogen atoms or the like; M represents iron, manganese or cobalt; X represents a counter ion; and n represents 1 or 2.) COPYRIGHT: (C)2015,JPOandINPIT