885-81-4

Basic information

• Product Name: N-(4-ethoxy-2-nitrophenyl)acetamide
• Synonyms: N-(4-ethoxy-2-nitrophenyl)acetamide;2'-Nitro-4'-ethoxyacetoanilide;4-Ethoxy-2-nitro-l-acetylaminobenzene
• CAS NO: 885-81-4
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.21328
• EINECS: 212-945-8
• Mol File: 885-81-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 438.4°C at 760 mmHg
• Flash Point: 218.9°C
• Appearance: /
• Density: 1.282g/cm³
• Vapor Pressure: 6.94E-08mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: N-(4-ethoxy-2-nitrophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-ethoxy-2-nitrophenyl)acetamide(885-81-4)
• EPA Substance Registry System: N-(4-ethoxy-2-nitrophenyl)acetamide(885-81-4)

Safety Data

• Hazardous Substances Data: 885-81-4(Hazardous Substances Data)

Usage

General Description

N-(4-ethoxy-2-nitrophenyl)acetamide is an organic compound containing a nitro group, an ethoxy group, and an acetamide functional group. Its molecular structure consists of a nitrophenyl ring with an ethoxy group attached to the 4-position and an acetamide group attached to the 2-position. This chemical has potential applications in the pharmaceutical industry due to its nitro and acetamide functionalities, which could be exploited for their biological activities. Its synthesis and properties make it a valuable molecule for understanding the chemical reactivity and behavior of similar nitrophenyl and acetamide compounds. Additionally, its use in medicinal chemistry could lead to the development of novel drugs with enhanced efficacy and reduced toxicity.

InChI:InChI=1/C10H12N2O4/c1-3-16-8-4-5-9(11-7(2)13)10(6-8)12(14)15/h4-6H,3H2,1-2H3,(H,11,13)

Upstream product

• 59255-66-2 N-(tert-butoxycarbonyl)-4-ethoxyaniline 
• 108-24-7 acetic anhydride 
• 156-43-4 4-Ethoxyaniline 
• 62-44-2 4-ethoxyacetanilide 
• 64-19-7 acetic acid 
• 64-17-5 ethanol 
• 56-23-5 tetrachloromethane 
• 7697-37-2 nitric acid 

Downstream Products

• 282547-59-5 6-ethoxy-8-nitro-quinoline 
• 35739-45-8 4-ethoxy-2-nitro-1-phenylamine 
• 72546-12-4 4-Ethoxy-2-aminobenzolsulfonsaeure 
• 72546-14-6 4-Ethoxy-benzol-disulfonsaeure-(1,2) 
• 72546-16-8 4-Ethoxy-benzol-disulfonsaeure-(1,2)-dichlorid 
• 52821-51-9 4-Ethoxy-1,2-dimercapto-benzol 
• 5437-99-0 6-hydroxy-8-nitroquinoline 
• 644984-33-8 8-Amino-6-ethoxy-chinolin 
• 858855-42-2 4-ethoxy-3-chloro-2-nitro-aniline 
• 846031-57-0 2-chloro-3-nitro-phenetole 
• 603-84-9 2-chloro-3-nitrophenol 
• 3914-05-4 4-ethoxy-2,3-dinitro-aniline 
• 873967-25-0 N,N'-(4-ethoxy-o-phenylene)-bis-acetamide 
• 118933-94-1 1-acetyl-5-ethoxybenzotriazole 

Relevant articles and documents

Visible-Light-Mediated Nitration of Protected Anilines

The photocatalytic nitration of protected anilines proceeds with riboflavin tetraacetate as an organic photoredox catalyst. Sodium nitrite serves as the NO2 source in this visible-light-driven room temperature reaction. Various nitroanilines are obtained in moderate to good yields without the addition of acid or stoichiometric oxidation agents. The catalytic cycle is closed by aerial oxygen as the terminal oxidant.

INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT

The present invention relates to a composition for preserving cells, tissues and organs, comprising as an active ingredient indole and indazole compounds of formula (1), or a pharmaceutically acceptable salt or isomer thereof, which are effective for preventing injury of organs, isolated cell systems or tissues caused by cold storage, transplant operation or post-transplantation reperfusion; a preservation method; and a preparation method of the composition.

GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT

The present invention relates to new compounds of formula (1) exhibiting excellent activity for glucokinase, and pharmaceutical compositions comprising the same as an active ingredient.