543740-74-5 Usage
Description
2-Iodo-6-nitro-4-(trifluoromethyl)aniline is an organic compound characterized by its molecular structure that features an iodine atom at the 2nd position, a nitro group at the 6th position, and a trifluoromethyl group at the 4th position attached to an aniline backbone. 2-Iodo-6-nitro-4-(trifluoromethyl)aniline is known for its reactivity and synthetic utility in the field of organic chemistry.
Uses
Used in Pharmaceutical Industry:
2-Iodo-6-nitro-4-(trifluoromethyl)aniline is used as a synthetic intermediate for the preparation of indoles and related heterocycles, which are important structural motifs found in a wide range of biologically active compounds, including pharmaceuticals. The base-catalyzed cyclization process allows for the efficient synthesis of these valuable molecules, contributing to the development of new drugs and therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 2-Iodo-6-nitro-4-(trifluoromethyl)aniline serves as a key building block for the synthesis of various complex organic molecules. Its unique functional groups and reactivity make it a valuable compound for exploring new reaction pathways and developing innovative synthetic strategies. 2-Iodo-6-nitro-4-(trifluoromethyl)aniline can be utilized in the design and synthesis of novel materials, catalysts, and other specialty chemicals with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 543740-74-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,3,7,4 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 543740-74:
(8*5)+(7*4)+(6*3)+(5*7)+(4*4)+(3*0)+(2*7)+(1*4)=155
155 % 10 = 5
So 543740-74-5 is a valid CAS Registry Number.
543740-74-5Relevant articles and documents
Perenosins: A new class of anion transporter with anti-cancer activity
Van Rossom, Wim,Asby, Daniel J.,Tavassoli, Ali,Gale, Philip A.
, p. 2645 - 2650 (2016/03/05)
A new class of anion transporter named 'perenosins' consisting of a pyrrole linked through an imine to either an indole, benzimidazole or indazole is reported. The indole containing members of the perenosin family function as effective transmembrane Cl-/NO3- antiporters and HCl cotransporters in a manner similar to the prodigiosenes. The compounds reduce the viability of MDA-MB-231 and MCF-7.
Mild Synthesis of Polyfunctional Benzimidazoles and Indoles by the Reduction of Functionalized Nitroarenes with Phenylmagnesium Chloride
Dohle, Wolfgang,Staubitz, Anne,Knochel, Paul
, p. 5323 - 5331 (2007/10/03)
Phenylmagnesium chloride has been used for the conversion of selected nitroarenes into nitrenes. Their insertion into a neighboring sp2 C-H bond yielded functionalized heterocycles. A novel and mild synthesis of polyfunctional benzimidazoles and indoles is described.
