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N-benzyl-2,3,4,5,6-pentahydroxyhexanamide, also known as sucralfate, is a complex organic compound with the chemical formula C12H21NO8. It is a derivative of sucrose, where the hydroxyl groups at the 2, 3, 4, 5, and 6 positions are replaced by hydroxyl groups, and a benzyl group is attached to the nitrogen atom. This medication is primarily used as an anti-ulcer agent, working by forming a protective layer on the stomach and duodenal mucosa to shield it from further irritation and promote healing. It is particularly effective in treating conditions like peptic ulcers and gastroesophageal reflux disease (GERD). Sucralfate is not absorbed systemically, which minimizes side effects, and it is generally well-tolerated by patients.

5438-33-5

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5438-33-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5438-33-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,3 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5438-33:
(6*5)+(5*4)+(4*3)+(3*8)+(2*3)+(1*3)=95
95 % 10 = 5
So 5438-33-5 is a valid CAS Registry Number.

5438-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-benzyl-2,3,4,5,6-pentahydroxyhexanamide

1.2 Other means of identification

Product number -
Other names D-gluconic acid benzylamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5438-33-5 SDS

5438-33-5Relevant academic research and scientific papers

Synthesis and evaluation of D-gluconamides as green mineral scales

Reis, Marcelo I.P.,Gon?alves, Aline D.,Da Silva, Fernando De C.,Jord?o, Alessandro K.,Alves, Ricardo J.,De Andrade, Saulo Fernandes,Resende, Jackson A.L.C.,Rocha, Anderson A.,Ferreira, Vitor F.

experimental part, p. 6 - 12 (2012/07/02)

A series of 13 d-gluconamides were synthesized in moderate to good yields and evaluated as green scale inhibitors. The crystal structures of two compounds were determined by X-ray crystallography. The compounds 6c and 6d showed a reasonable inhibition of BaSO4 precipitation from aqueous solution (47% and 51%, respectively) that indicated the potential for these derivatives of δ-gluconolactone.

Direct amidation of aldoses and decarboxylative amidation of α-keto acids: An efficient conjugation method for unprotected carbohydrate molecules

Cho, Chia-Ching,Liu, Jia-Nan,Chien, Chung-Hsun,Shie, Jiun-Jie,Chen, Ying-Chu,Fang, Jim-Min

supporting information; experimental part, p. 1549 - 1556 (2009/07/24)

With use of iodine as an appropriate oxidant, unprotected and unmodified aldoses undergo oxidative amidation with a variety of functionalized amines, a-amino esters, and peptides, whereas KDO, sialic acid, and other a-keto acids proceed with oxidative dec

Synthesis of crosslinked nanostructured saccharidic vinyl copolymers and their functionalization

Bertini, Vincenzo,Pocci, Marco,Alfei, Silvana,Idini, Barbara,Lucchesini, Francesco

, p. 11672 - 11680 (2008/03/13)

Saccharidic monomers and a macromonomer were synthesized and copolymerized in the presence of divinylbenzene (DVB) as crosslinker in conditions of separation of phases to give hydrophilic nanostructured sugar-based vinyl copolymers. Appropriate model molecules such as N-benzyl-d-gluconamide for the saccharidic copolymers and 4-(4-chlorobutoxy)benzaldehyde and (E)-4-(4-chloro-2-butenyloxy)benzaldehyde for electrophilic reagents prefiguring possible copper amine oxidase inhibitors allowed identification of conditions for useful monofunctionalizations mainly at the position 2 of the saccharidic units. The examined samples of the nanostructured copolymers from one of the monomers proved to be stable enough to tolerate the functionalization reactions without loss of morphology.

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