54397-17-0

Basic information

• Product Name: 4-Thiazolidinone, 3-(4-chlorophenyl)-2-phenyl-
• CAS NO: 54397-17-0
• Molecular Formula: C15H12ClNOS
• Molecular Weight: 289.785
• Mol File: 54397-17-0.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 4-Thiazolidinone, 3-(4-chlorophenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolidinone, 3-(4-chlorophenyl)-2-phenyl-(54397-17-0)
• EPA Substance Registry System: 4-Thiazolidinone, 3-(4-chlorophenyl)-2-phenyl-(54397-17-0)

Safety Data

• Hazardous Substances Data: 54397-17-0(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 100-52-7 benzaldehyde 
• 68-11-1 mercaptoacetic acid 
• 1613-89-4 (E)-N-benzylidene-4-chloroaniline 
• 126079-77-4 [(4-Chloro-phenylamino)-phenyl-methylsulfanyl]-acetic acid 
• 780-21-2 N-(4-chlorobenzylidene)aniline 

Downstream Products

• 117664-65-0 [6-(4-Chloro-phenyl)-5-phenyl-5,6-dihydro-[1,3]dithiolo[4,5-d]thiazol-(2E)-ylidene]-(4-fluoro-phenyl)-amine 
• 117664-69-4 [6-(4-Chloro-phenyl)-5-phenyl-5,6-dihydro-1-oxa-3,4-dithia-6-aza-pentalen-(2E)-ylidene]-(4-fluoro-phenyl)-amine 
• 117664-61-6 (4-Fluoro-phenyl)-dithiocarbamic acid 3-(4-chloro-phenyl)-4-oxo-2-phenyl-thiazolidin-5-yl ester 
• 117682-44-7 4-(4-Chloro-phenyl)-3-(4-fluoro-phenyl)-5-phenyl-4,5-dihydro-3H-thiazolo[4,5-d]thiazole-2-thione 
• 117664-58-1 5-Bromo-3-(4-chloro-phenyl)-2-phenyl-thiazolidin-4-one 
• 54690-98-1 3-(4-chloro-phenyl)-5-(4-dimethylamino-benzylidene)-2-phenyl-thiazolidin-4-one 

Relevant articles and documents

CoFe2O4@SiO2/PrNH2 nanoparticles as highly efficient and magnetically recoverable catalyst for the synthesis of 1,3-thiazolidin-4-ones

An efficient three-component synthesis of 1,3-thiazolidin-4-ones is described by one-pot condensation of aldehydes, aromatic amine and thioglycolic acid with nano-CoFe2O4@SiO2/PrNH2 as a robust heterogeneous catalyst. The significant advantages of this protocol are the use of magnetically recoverable catalyst, high to excellent product yields, operational simplicity and the use of CoFe2O4@SiO2/PrNH2 nanoparticles as an environment-friendly catalyst.

Visible-light-driven photocatalytic activity of ZnO/g-C3N4 heterojunction for the green synthesis of biologically interest small molecules of thiazolidinones

Designing a photocatalytic system with complementary properties including high surface area, high loading, extraordinary electronic properties, and easy separation for increases photocatalytic performance has remained a challenge in photocatalytic applications. Herein, an environmentally benign approach was developed to fabricate graphitic carbon nitride (g-C3N4) decorated with nanorods zinc oxide (ZnO). The photocatalytic activity of ZnO decorated on the g-C3N4 surface was developed in the synthesis of 1,3-thiazolidin-4-ones and bis-thiazolidinones under very mild and sustainable reaction conditions. The reaction can be carried out by utilizing visible light without the requirement of any additive and other external sources of energy. It was found that the proposed photocatalyst is a more facile, recyclable, large-scale application and provides some new insights into the stabilization of semiconductors for a variety of applications.

TS-1 zeolite as a Lewis acid catalyst for solvent-free one-pot synthesis of 1,3-thiazolidin-4-ones

Abstract: Titanium silicate (TS-1) zeolite heterogeneous catalyst is synthesized by the hydrothermally discontinuous method and is characterized by using XRD, SEM, TEM, and NH3–TPD techniques. The catalytic activity of the TS-1 type zeolite was tested for one-pot solvent-free synthesis of 1,3-thiazolidine-4-ones. The present technique illustrates many benefits, including eco-friendly reaction conditions, environmentally helpful, short response time, simplicity, straightforward separatation, catalyst reusability and high yields of the products. Furthermore, the catalyst was utilized for four recycle reactions and it has been found that the catalyst shows consistent chemical process activity. Graphical abstract: [Figure not available: see fulltext.].