5441-60-1

Usage

Uses

Used in Pharmaceutical Industry:
N-methyl-1-(2-nitrophenyl)methanamine is used as a synthetic intermediate for the development of new drugs. Its unique structure and reactivity make it a valuable building block in the synthesis of various organic compounds with potential therapeutic applications.
Used in Chemical Industry:
N-methyl-1-(2-nitrophenyl)methanamine is used as a precursor in the synthesis of various organic compounds. Its aromatic amine and nitro groups provide opportunities for further chemical reactions and modifications, making it a versatile compound in the chemical industry.
Used in Material Development:
Due to its unique structure and reactivity, N-methyl-1-(2-nitrophenyl)methanamine may be used in the development of new materials with specific properties. Its potential applications in this field could include the creation of novel polymers, dyes, or other functional materials with desired characteristics.

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 593-51-1 methylamine hydrochloride 
• 57707-11-6 Methyl-[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-amine 
• 612-23-7 2-nitrobenzyl chloride 
• 74-89-5 methylamine 

Downstream Products

• 211619-36-2 N-methyl-N-(2-nitrobenzyl)carbamoyl chloride 
• 1283519-43-6 C₁₇H₁₉ClN₂O₂ 
• 1904-71-8 2-amino-N-methylbenzylamine hydrochloride 

Relevant academic research and scientific papers

Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II

Convenient synthetic routes to KN-93, N-(2-{[[(2E)-3-(4-chlorophenyl)prop- 2-enyl](methyl)amino]methyl}phenyl)-N-(2-hydroxyethyl)-4- methoxybenzenesulfonamide, a well-known Ca2+/calmoduline-dependent protein kinase II (CaMKII) inhibitor, are de

POTENTIAL CNS ACTIVE 1-ARYL-2-AMINO-1-ETHANOL DERIVATIVES

New N-(picolyl)-2-(methylamino)-1-aryl-1-ethanols (I) and their O-acyl derivatives (II) were synthesized.Their dopaminomimetic and antidepressant biological activities were examined and compared with the activities of N-(2-aminobenzyl)-2-(methylamino)-1-aryl-1-ethanols (III).It was established that in the reaction of N- methylamine (2) and styryl oxide, the two directions of the splitting of the epoxide ring give rise to two different products that were isolated and identified in the form of their O-acetyl derivatives (13 and 15, respectively).

A Convenient Preparation of 3-Methyl-3,4-dihydro-2(1H)-quinazolinone

3-Methyl-3,4-dihydro-2(1H)-quinazolinone (5) can be prepared in good yield and quality from o-nitrobenzyl chloride (1).The three-step sequence requires no purification of intermediates or final product.