54419-22-6

Basic information

• Product Name: 1-(3,4-dimethoxyphenyl)butan-1-ol
• CAS NO: 54419-22-6
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.2695
• Mol File: 54419-22-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 316.3°C at 760 mmHg
• Flash Point: 145.1°C
• Density: 1.043g/cm³
• Vapor Pressure: 0.000175mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: 1-(3,4-dimethoxyphenyl)butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dimethoxyphenyl)butan-1-ol(54419-22-6)
• EPA Substance Registry System: 1-(3,4-dimethoxyphenyl)butan-1-ol(54419-22-6)

Safety Data

• Hazardous Substances Data: 54419-22-6(Hazardous Substances Data)

Usage

Description

1-(3,4-dimethoxyphenyl)butan-1-ol is a chemical compound characterized by the molecular formula C12H18O3. It is an organic compound featuring a long carbon chain and a hydroxyl functional group. The presence of a 3,4-dimethoxyphenyl group in its structure indicates potential pharmacological properties, as similar compounds have been explored for their medicinal uses.

Uses

Used in Pharmaceutical Industry:
1-(3,4-dimethoxyphenyl)butan-1-ol is used as a potential candidate for the development of new drugs due to its chemical structure and the presence of a 3,4-dimethoxyphenyl group, which may contribute to its pharmacological properties.
Used in Fragrance and Flavor Production:
1-(3,4-dimethoxyphenyl)butan-1-ol is used as a potential ingredient in the production of fragrances or flavors, leveraging its aromatic properties. However, further research and testing are required to fully comprehend its properties and potential applications in these areas.

Upstream product

• 54419-21-5 1-(3,4-dimethoxyphenyl)butan-1-one 
• 2234-82-4 1-propylmagnesium chloride 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 91-16-7 1,2-dimethoxybenzene 
• 16613-23-3 3,4-Dimethoxyphenyl-2-piperidinopropyl-keton 
• 106-94-5 propyl bromide 
• 927-77-5 n-propylmagnesium bromide 

Downstream Products

• 76252-28-3 trans-4-(3′,4′-dimethoxyphenyl)but-3-ene 

Relevant articles and documents

Euodenine A: A small-molecule agonist of human TLR4

A small-molecule natural product, euodenine A (1), was identified as an agonist of the human TLR4 receptor. Euodenine A was isolated from the leaves of Euodia asteridula (Rutaceae) found in Papua New Guinea and has an unusual U-shaped structure. It was synthesized along with a series of analogues that exhibit potent and selective agonism of the TLR4 receptor. SAR development around the cyclobutane ring resulted in a 10-fold increase in potency. The natural product demonstrated an extracellular site of action, which requires the extracellular domain of TLR4 to stimulate a NF-κB reporter response. 1 is a human-selective agonist that is CD14-independent, and it requires both TLR4 and MD-2 for full efficacy. Testing for immunomodulation in PBMC cells shows the induction of the cytokines IL-8, IL-10, TNF-α, and IL-12p40 as well as suppression of IL-5 from activated PBMCs, indicating that compounds like 1 could modulate the Th2 immune response without causing lung damage.

AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS

The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.

Further characterization of the constituents of a Thai medicinal plant, Zingiber cassumunar Roxb

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