5443-52-7 Usage
Chemical Category
2-(methylamino)-4-phenylbutanoic acid belongs to the category of amino acids.
Molecular Weight
The molecular weight of 2-(methylamino)-4-phenylbutanoic acid is 193.24 g/mol.
Physical Appearance
2-(methylamino)-4-phenylbutanoic acid is a white crystalline powder.
Melting Point
The melting point of 2-(methylamino)-4-phenylbutanoic acid is 145-147°C.
Use in Synthesis
2-(methylamino)-4-phenylbutanoic acid is an important intermediate in the synthesis of pharmaceuticals and can be used as a building block for the production of various drugs.
Role in Medicinal Chemistry
This chemical is commonly used in medicinal chemistry and drug development processes due to its role as a precursor in the synthesis of biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 5443-52-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5443-52:
(6*5)+(5*4)+(4*4)+(3*3)+(2*5)+(1*2)=87
87 % 10 = 7
So 5443-52-7 is a valid CAS Registry Number.
5443-52-7Relevant articles and documents
Biocatalytic Synthesis of Chiral N-Functionalized Amino Acids
Hyslop, Julia F.,Lovelock, Sarah L.,Sutton, Peter W.,Brown, Kristin K.,Watson, Allan J. B.,Roiban, Gheorghe-Doru
supporting information, p. 13821 - 13824 (2018/09/27)
N-Functionalized amino acids are important building blocks for the preparation of diverse bioactive molecules, including peptides. The development of sustainable manufacturing routes to chiral N-alkylated amino acids remains a significant challenge in the pharmaceutical and fine-chemical industries. Herein we report the discovery of a structurally diverse panel of biocatalysts which catalyze the asymmetric synthesis of N-alkyl amino acids through the reductive coupling of ketones and amines. Reactions have been performed on a gram scale to yield optically pure N-alkyl-functionalized products in high yields.
