54433-86-2Relevant academic research and scientific papers
Botrylactone: New interest in an old molecule - Review of its absolute configuration and related compounds
Moraga, Javier,Pinedo, Cristina,Durán-Patrón, Rosa,Collado, Isidro G.,Hernández-Galán, Rosario
experimental part, p. 417 - 420 (2011/03/19)
The absolute configuration of botrylactone, a unique compound with an interesting polyketide lactone skeleton with two oxirane bridges previously isolated from Botrytis cinerea and described as a powerful antibiotic, has been reviewed on the basis of sign of the optical rotation, NOE experiments and NMR method. The isolation of 7-deoxybotrylactone and 5-hydroxy-7-(4-hydroxydec-2(3)- enoyl) botrylactone enables us to characterize an intriguing new family of compounds with this interesting polyketide skeleton. A common biosynthetic origin with botcinin derivatives is proposed. Copyright
Studies on the biosynthesis of secobotryane skeleton
Durán-Patrón, Rosa,Colmenares, Ana J.,Montes, Antonio,Hanson, James R.,Hernández-Galán, Rosario,Collado, Isidro G.
, p. 6267 - 6271 (2007/10/03)
The labelling and coupling patterns of secobotrytrienediol, biosynthesised from [1-13C] and [1,2-13C2]-acetate by the fungus Botrytis cinerea, have been used to define the mode of formation and the biogenetic origin of secobotrytrienediol. [10-2H]-Botrydiol was not incorporated into the secobotryane skeleton. In addition, this feeding experiment led to the isolation of three new unlabelled derivatives possessing a secobotryane skeleton, secobotrydiene-3,10,15-triol, secobotrydiene-3,4,10,15-tetraol, and secobotrytriene-10,12,15-triol.
