54986-75-3

Usage

Uses

Used in Pharmaceutical Applications:
Botrydial is used as a cytotoxic agent for its ability to target and disrupt cellular processes in cancer cells. Its potent cytotoxic properties make it a promising candidate for the development of new cancer treatments, particularly in targeting rapidly dividing cells that are characteristic of various types of cancer.
Used in Research Applications:
In the field of research, botrydial is utilized as a tool to study the mechanisms of cell death and the effects of cytotoxic compounds on cellular processes. Its ability to interfere with cellular functions can provide valuable insights into the development of novel therapeutic strategies and the understanding of cellular responses to various stimuli.
Used in Drug Development:
Botrydial's cytotoxic properties also make it a potential candidate for the development of new drugs targeting specific diseases and conditions. Researchers can explore its potential in creating targeted therapies that exploit the compound's ability to disrupt cellular processes, leading to the development of more effective treatments for a range of diseases.

InChI:InChI=1/C17H26O5/c1-10-6-13(22-11(2)20)14-15(3,4)8-16(5,9-19)17(14,21)12(10)7-18/h7,9-10,12-14,21H,6,8H2,1-5H3/t10-,12+,13+,14+,16-,17-/m1/s1

Upstream product

• 5706-12-7 2-benzylidine-1-indanone 

Downstream Products

• 78433-22-4 botrydiol 
• 97165-23-6 botrydienal 
• 54433-86-2 dihydrobotrydial 
• 97165-24-7 dehydrobotrydienal 
• 503858-43-3 (1S,3aR,4S,6R,7S,7aS)-4-Acetoxy-7a-hydroxy-1,3,3,6-tetramethyl-octahydro-indene-1,7-dicarboxylic acid 
• 73233-08-6 (1S,3aR,4S,6R,7S,7aS)-4-Acetoxy-7a-hydroxy-1,3,3,6-tetramethyl-octahydro-indene-1,7-dicarboxylic acid dimethyl ester 
• 75207-23-7 methyl botryaloate 
• 75207-22-6 methyl acetylbotryaloate 
• 609853-29-4 C₁₇H₂₉⁽²⁾HO₅ 

Relevant academic research and scientific papers

The role of botrydienediol in the biodegradation of the sesquiterpenoid phytotoxin botrydial by Botrytis cinerea

The biotransformation of botrydienediol (6) labelled with deuterium on carbons C-10 and C-15 has been studied. This has led to modification of some previous assumptions about the biodegradative route of botrydial. The [10-2H,15-2H]-botry-1(9)-4-diendiol (12) was transformed into dehydrobotrydienediol derivatives 13-15 but it was not incorporated into secobotryane skeleton (7). In addition, three new sesquiterpenoids have been isolated, which shed further light on the secondary metabolites of Botrytis cinerea. From the point of view of persistence of these toxins in the food chain, the easy biotransformation and different biodegradative routes of botrydial (1), seem to indicate that the toxin may not persist in the plant for a long time as it will be metabolized by the fungi and the plant.

Botrylactone: New interest in an old molecule - Review of its absolute configuration and related compounds

The absolute configuration of botrylactone, a unique compound with an interesting polyketide lactone skeleton with two oxirane bridges previously isolated from Botrytis cinerea and described as a powerful antibiotic, has been reviewed on the basis of sign of the optical rotation, NOE experiments and NMR method. The isolation of 7-deoxybotrylactone and 5-hydroxy-7-(4-hydroxydec-2(3)- enoyl) botrylactone enables us to characterize an intriguing new family of compounds with this interesting polyketide skeleton. A common biosynthetic origin with botcinin derivatives is proposed. Copyright