54443-82-2

Basic information

• Product Name: 2,4-dimethyl-cinnamyl alcohol
• Synonyms: 2,4-dimethyl-cinnamyl alcohol
• CAS NO: 54443-82-2
• Molecular Weight: 162.232
• Mol File: 54443-82-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4-dimethyl-cinnamyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethyl-cinnamyl alcohol(54443-82-2)
• EPA Substance Registry System: 2,4-dimethyl-cinnamyl alcohol(54443-82-2)

Safety Data

• Hazardous Substances Data: 54443-82-2(Hazardous Substances Data)

Upstream product

• 15764-16-6 2,4-dimethylbenzaldehyde 
• 61052-15-1 (E)-ethyl 3-(2,4-dimethylphenyl)acrylate 
• 1685-80-9 2,4-dimethylcinnamic acid 

Downstream Products

• 1137837-95-6 tert-butyl (E)-3-(2',4'-dimethylphenyl)prop-2-en-1-yl carbonate 
• 1359827-76-1 (R)-dimethyl 2-(1-(2,4-dimethylphenyl)-3-oxopropyl)malonate 

Relevant articles and documents

Method for synthesizing photoactive bromohydrin compound

The invention discloses a method for synthesizing a photoactive bromohydrin compound, which comprises the following steps: reacting cinnamyl alcohol as shown in a formula I, benzamide bromide as shown in a formula II, a quinine derivative, L-camphorsulfonic acid and water in a first organic solvent to obtain the bromohydrin compound as shown in a formula III. According to the method, raw materials are easy to synthesize, reaction conditions are mild, operation is easy and convenient, the yield reaches up to 47%-87%, enantioselectivity can generally reach 80% or above, and the highest point can even reach 95%.

A Simple and Efficient Access to Naphtho[b]furans by Claisen Rearrangement/Cyclization of Bromonaphthyl 3-Phenylallyl Ethers

A transition-metal-free Claisen rearrangement/cyclization reaction was developed for the synthesis of naphthofuran derivatives from bromonaphthyl 3-phenylallyl ethers. The nature of the base employed in this reaction plays an important role in determining the ratio for the formation of naphthofuran and naphthol products. By using K2CO3 as base and DMF as solvent, we have synthesized a variety of functionalized naphthofurans in good to high yields (49-92 %) and with satisfactory selectivities.