54458-33-2

Upstream product

• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 
• 54458-30-9 2-bromo-1-(4-methylphenyl)-3-phenyl-1,3-propanedione 
• 10325-65-2 2,3-Dibromo-3-phenyl-1-p-tolyl-propan-1-one 
• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 27729-96-0 1-phenyl-3-(p-methylphenyl)-2,3-epoxy-1-propanone 

Relevant academic research and scientific papers

LiBr/β-CD/IBX/H2O-DMSO: A new approach for one-pot biomimetic regioselective ring opening of chalcone epoxides to bromohydrins and conversion to 1,2,3-triketones

Highly regioselective ring cleavage of chalcone epoxides to bromohydrins has been carried out in good yields with LiBr in the presence of β-CD using DMSO-H2O as solvent system. The ring-opened product, i.e., bromohydrin, was well adapted to IBX-mediated oxidation in such a fashion that the bromohydrins are transformed to their corresponding 1,2,3-triketones in moderate-to-good yields in one pot.