54467-34-4

Basic information

• Product Name: 2-Pyridinemethanol, a-phenyl-a-2-pyridinyl-
• CAS NO: 54467-34-4
• Molecular Formula: C17H14N2O
• Molecular Weight: 262.311
• Mol File: 54467-34-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Pyridinemethanol, a-phenyl-a-2-pyridinyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanol, a-phenyl-a-2-pyridinyl-(54467-34-4)
• EPA Substance Registry System: 2-Pyridinemethanol, a-phenyl-a-2-pyridinyl-(54467-34-4)

Safety Data

• Hazardous Substances Data: 54467-34-4(Hazardous Substances Data)

Upstream product

• 93-89-0 benzoic acid ethyl ester 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 
• 108-86-1 bromobenzene 
• 19437-26-4 2,2'-dipyridyl ketone 
• 93321-14-3 2-(1-naphthyl)benzyl alcohol 
• 100-58-3 phenylmagnesium bromide 
• 17624-36-1 2-pyridyllithium 
• 5029-67-4 2-iodopyridine 
• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 79057-57-1 α,α-bis(pyridin-2-yl)toluene 

Downstream Products

• 79057-57-1 α,α-bis(pyridin-2-yl)toluene 
• 1316276-71-7 2,2'-((4'-(2-(pyridin-4-yl)ethyl)biphenyl-4-yl)methylene)dipyridine 
• 1316276-72-8 2,2'-(fluoro(phenyl)methylene)dipyridine 
• 1427443-49-9 [Pt(COMe)₂{(2-pyridyl)₂PhCOH}] 

Relevant articles and documents

Mechanistically Driven Control over Cubane Oxo Cluster Catalysts

Predictive and mechanistically driven access to polynuclear oxo clusters and related materials remains a grand challenge of inorganic chemistry. We here introduce a novel strategy for synthetic control over highly sought-after transition metal {M4/s

Transition-Metal Free Chemoselective Hydroxylation and Hydroxylation-Deuteration of Heterobenzylic Methylenes

We developed an approach for direct selective hydroxylation of heterobenzylic methylenes to secondary alcohols avoiding overoxidation to ketones by using a KOBu-t/DMSO/air system. Most reactions could reach completion in several minutes to give hydroxylated products in 41-76% yields. Using DMSO-d6, this protocol resulted in difunctionalization of heterobenzylic methylenes to afford α-deuterated secondary alcohols (>93% incorporation). By employing this method, active pharmaceutical ingredients carbinoxamine and doxylamine were synthesized in two steps in moderate yields.

MELANIN PRODUCTION INHIBITOR

Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor is represented by general formula (1) (excluding clotrimazole) and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent. At least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group. When one of R1 and R2 is an oxo group, the other is not present. R3 is selected from a hydrogen atom, and a C1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms. The number of R3's present in the compound corresponds to X and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.