544694-57-7

Basic information

• Product Name: 4-{4-[(3'-carbamimidoyl-biphenyl-4-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-{4-[(3'-carbamimidoyl-biphenyl-4-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 544694-57-7
• Molecular Weight: 578.733
• Mol File: 544694-57-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{4-[(3'-carbamimidoyl-biphenyl-4-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{4-[(3'-carbamimidoyl-biphenyl-4-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester(544694-57-7)
• EPA Substance Registry System: 4-{4-[(3'-carbamimidoyl-biphenyl-4-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester(544694-57-7)

Safety Data

• Hazardous Substances Data: 544694-57-7(Hazardous Substances Data)

Upstream product

• 454437-33-3 N-{4-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]phenyl}methanesulfonamide 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 
• 135689-88-2 4'-bromomethyl-biphenyl-3-carbonitrile 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 150255-96-2 (3‐cyanophenyl)boronic acid 
• 350-46-9 4-Fluoronitrobenzene 
• 133909-96-3 4'-methyl-[1,1'-biphenyl]-3-carbonitrile 
• 106-38-7 para-bromotoluene 

Relevant articles and documents

Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors

A series of benzoxazinone derivatives was designed and synthesized as factor Xa inhibitors. We demonstrated that the naphthyl moiety in the aniline-based compounds 1 and 2 can be replaced with benzene-fused heterobicycles and biaryls to give factor Xa inh