5448-01-1

Usage

Uses

Used in Pharmaceutical Research:
(2,3-diphenyl-1H-indol-1-yl)(phenyl)methanone is used as a research compound for investigating its potential applications in the development of drugs for various medical conditions. Its unique structure and pharmacological properties make it a promising candidate for further research and development.
Used in Organic Synthesis:
(2,3-diphenyl-1H-indol-1-yl)(phenyl)methanone is used as a synthetic intermediate in the preparation of other organic compounds. Its versatile structure allows for the synthesis of various derivatives with potential applications in different fields.
Used in Drug Development for Cancer:
(2,3-diphenyl-1H-indol-1-yl)(phenyl)methanone is used as a potential drug candidate for the development of cancer treatments. Its unique structure and pharmacological properties make it a promising candidate for further research and development in this area.
Used in Drug Development for Depression:
(2,3-diphenyl-1H-indol-1-yl)(phenyl)methanone is used as a potential drug candidate for the development of treatments for depression. Its unique structure and pharmacological properties make it a promising candidate for further research and development in this area.

Upstream product

• 3469-20-3 2,3-diphenyl-1H-indole 
• 98-88-4 benzoyl chloride 
• 117785-92-9 Benzoic acid N'-[1,2-diphenyl-eth-(Z)-ylidene]-N-phenyl-hydrazide 
• 93-98-1 N-phenyl benzoyl amide 
• 501-65-5 diphenyl acetylene 
• 1239-56-1 1-(2,3-diphenyl-1H-indol-1-yl)ethan-1-one 

Downstream Products

• 3469-20-3 2,3-diphenyl-1H-indole 
• 117788-15-5 1-benzyl-2,3-diphenyl-1H-indole 
• 1741-98-6 6-nitro-2,3-diphenyl-indole 

Relevant academic research and scientific papers

Oxidative annulation of anilides with internal alkynes using an (Electron-Deficient η5-cyclopentadienyl)rhodium(III) catalyst under ambient conditions

A dinuclear (electron-deficient η5-cyclopentadienyl) rhodium(III) complex was synthesized on a preparative scale via the rhodium-catalyzed cross [2+2+1] cyclotrimerization of silylacetylenes and two alkynyl esters, leading to substituted silylf

Diborane as reducing agent: Part VII - Novel reduction of indole-1-ketones to 1-alylindoles to 1-alkylindoles and mechanism of reduction of indole-1-aldehydes and ketones

Borane/THF reduction of nine indole-1-ketones (1a-1i) forms 1-ethylindoles (6a-6h) and the 1-benzylindole (6i) in 50-80percent yields.The ketones 1h and 1i, each of which bears phenyl groups at positions 2 and 3, also undergo deacylation to furnish 2,3-diphenylindole (8) in ca. 40percent yield.The mechanism of formation of both 8 and 6a-6i have been rationalised.The rate of borane/THF reduction of 1 is apparently slower than that of indole-1-carboxaldehydes (9).An attempt has been made to throw some light on the cause of this difference.

Indolization by Phosphorus Trichloride of Functionalized Ketone Arylhydrazones: Synthesis of Pharmacological Interesting Indoles

The synthesis of indoles starting from phosphorus trichloride and arylhydrazones either functionalized in the ketone entity or N-substituted is reported.The reaction, carried out at room temperature, allows several substituents on the ketone framework of the hydrazone (e.g. ether, alkoxycarbonyl, halogeno, dialkylamino, olefinic, and phosphonic).Under optimum conditions high product yields were obtained.Evidence for the proposed mechanism is also reported.