73855-45-5

Basic information

• Product Name: 6-Chloro-1,2,3,4-tetrahydro-quinoxaline
• Synonyms: 6-Chloro-1,2,3,4-tetrahydro-quinoxaline;Brn 0135422;Quinoxaline, 1,2,3,4-tetrahydro-6-chloro-;Quinoxaline, 6-chloro-1,2,3,4-tetrahydro-
• CAS NO: 73855-45-5
• Molecular Formula: C₈H₉ClN₂
• Molecular Weight: 168.63
• Mol File: 73855-45-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 112-114 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 304.2°C at 760 mmHg
• Flash Point: 137.8°C
• Appearance: /
• Density: 1.202g/cm³
• Vapor Pressure: 0.000885mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 2-8°C
• PKA: 3?+-.0.70(Predicted)
• CAS DataBase Reference: 6-Chloro-1,2,3,4-tetrahydro-quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-1,2,3,4-tetrahydro-quinoxaline(73855-45-5)
• EPA Substance Registry System: 6-Chloro-1,2,3,4-tetrahydro-quinoxaline(73855-45-5)

Safety Data

• Hazardous Substances Data: 73855-45-5(Hazardous Substances Data)

Usage

General Description

6-Chloro-1,2,3,4-tetrahydro-quinoxaline is a chemical compound that is a derivative of quinoxaline. It is a heterocyclic organic compound with a chloro group attached to it. 6-Chloro-1,2,3,4-tetrahydro-quinoxaline is mainly used in pharmaceutical research for the development of potential drugs due to its interesting biological properties and potential therapeutic applications. It also has applications in organic synthesis as a building block for the synthesis of more complex compounds. Overall, 6-Chloro-1,2,3,4-tetrahydro-quinoxaline is a versatile and important chemical compound with potential applications in various fields including medicine and chemical research.

InChI:InChI=1/C8H9ClN2/c9-6-1-2-7-8(5-6)11-4-3-10-7/h1-2,5,10-11H,3-4H2

Upstream product

• 95-83-0 4-Chloro-1,2-phenylenediamine 
• 106-93-4 ethylene dibromide 
• 19853-64-6 6,7‐dichloroquinoxaline 
• 6639-79-8 6-chloroquinoxaline-2,3(1H,4H)-dione 
• 5448-43-1 6-chloroquinoxaline 

Relevant articles and documents

Tetrabutylammonium Bromide-Catalyzed Transfer Hydrogenation of Quinoxaline with HBpin as a Hydrogen Source

A metal-free environmentally benign, simple, and efficient transfer hydrogenation process of quinoxaline has been developed using the HBpin reagent as a hydrogen source. This reaction is compatible with a variety of quinoxalines offering the desired tetrahydroquinoxalines in moderate-to-excellent yields with Bu4NBr as a noncorrosive and low-cost catalyst.

New V1a receptor antagonist. Part 1. Synthesis and SAR development of urea derivatives

Solid preclinical evidence links vasopressin to social behavior in animals, so, extensive work has been initiated to find new vasopressin V1a receptor antagonists which can improve deteriorated social behavior in humans and can treat the core symptoms of

Rhodium-catalyzed transfer hydrogenation of quinoxalines with water as a hydrogen source

Rhodium-catalyzed transfer hydrogenation of quinoxalines with water as a hydrogen source was reported. The reaction allowed the simple preparation of tetrahydroquinoxalines under mild conditions. The deuterium-labelling experiment confirmed that water is