545-57-3Relevant academic research and scientific papers
THE MECHANISM OF THE FORMATION OF OXONITINE BY PERMANGANATE OXIDATION OF ACONITINE
Amiya, Takashi,Kanaiwa, Yoshio,Bando, Hideo,Suginome, Harusada
, p. 859 - 860 (1984)
An isotopic labeling study has shown that the N-formyl group of oxonitine, a product of permanganate oxidation of aconitine in a 95:5 acetone-water, originates from the methylene group of the N-ethyl of aconitine.
OXONITINE REVISITED: ITS MECHANISM OF FORMATION FROM ACONITINE
Kulanthaivel, Palaniappan,Pelletier, S. William
, p. 2351 - 2354 (2007/10/02)
Oxidation of aconitine (2) to oxonitine (1) with KMnO4 proceeds by three mechanisms, involving the CH3 and CH2 carbons of the N-ethyl group and the carbon of the solvent as sources of the N-CHO group of oxonitine.
AN UNUSUAL OXIDATION OF AN N-CH3 GROUP TO AN N-CHO GROUP BY OSMIUM TETROXIDE
Pelletier, S. William,Desai, Haridutt K.,Finer-Moore, Janet,Mody, Naresh V.
, p. 4229 - 4232 (2007/10/02)
Treatment of pyrodelphinine (1) with osmium tetroxide afforded a mixture of the cis-hydroxylation product 2 and an unexpected product 3 in the ratio of 4:1, respectively.Similarly, oxidation of delphinine (5) afforded α-oxodelphinine (6; 75percent) and oxidation of mesaconitine (8) furnished oxonitine (9; 92percent).Thus a very selective oxidation of the N-methyl group of delphinine and mesaconitine is effected by osmium tetroxide.
