54525-19-8

Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 4010735 is used as a key intermediate for the biosynthesis of phenolic compounds and anthraquinones, which have potential applications in the development of pharmaceutical products. These compounds possess various biological activities, such as antioxidant, anti-inflammatory, and antimicrobial properties, making them valuable for the creation of new drugs and therapies.
Used in Natural Products Industry:
CHEMBRDG-BB 4010735 is used as a precursor in the production of flavonoids and other polyphenolic compounds, which are widely used in the natural products industry. These compounds are known for their health-promoting properties, such as antioxidant, anti-inflammatory, and anticancer activities. They are commonly found in dietary supplements, functional foods, and cosmetics.
Used in Plant Defense Mechanisms:
CHEMBRDG-BB 4010735 is used as a key intermediate in the biosynthetic pathway for phenylpropanoids, which play a crucial role in plant defense mechanisms. Phenylpropanoids are involved in the production of secondary metabolites that help protect plants from pathogens, pests, and environmental stressors.
Used in Cell Wall Construction:
CHEMBRDG-BB 4010735 is used as an essential component in the biosynthesis of phenylpropanoids, which contribute to the structural integrity and stability of plant cell walls. These cell walls provide mechanical support, protection, and facilitate communication between cells, ensuring proper growth and development of plants.

InChI:InChI=1/C8H17NO/c1-2-9-5-3-4-8(6-9)7-10/h8,10H,2-7H2,1H3

Upstream product

• 136866-86-9 N-acetyl-3-acetoxymethylpiperidine 
• 4606-65-9 3-(hydroxymethy)piperidine 
• 74-96-4 ethyl bromide 
• 75-03-6 ethyl iodide 
• 57487-93-1 ethyl 1-ethylpiperidine-3-carboxylate 

Downstream Products

• 213416-83-2 2-amino-benzoic acid 1-ethyl-piperidin-3-ylmethyl ester 
• 1415596-24-5 C₃₃H₃₇ClN₂O₂S 
• 1415596-28-9 C₃₃H₃₇ClN₂O₂S 
• 1415596-16-5 C₃₃H₃₇ClN₂O₂S 
• 1415596-20-1 C₃₃H₃₇ClN₂O₂S 

Relevant academic research and scientific papers

NOVEL ADENINE DERIVATIVES

Compounds of formula (I) wherein R1 is C1-6alkylamino, or C1-6alkoxy; R2 is a group having the structure (II): n is an integer having a value of 1 to 6; Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the -(CH2)n- moiety at any carbon atom of the heterocycle; R3 is hydrogen, C1-8alkyl, or C3-7cycloalkylC0-6alkyl; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.

HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS

Compounds of formula (I) Q-L-W-C(=X)-Z-P wherein Q is an amine of the formula-N (R1)(R2); L is an alkyl or heterocyclyl-alkyl linker; W is a 6-or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 which are linked to groups L and C(X) respectively and Y1 and Y2 are independently selected from N and C; X is O, N, N-CN or S; Z is NR 3; P is an optionally substituted monocyclic or bicyclic aryl or heteroaryl group; and pharmaceutically acceptable salts or solvates thereof, are useful in the treatment of C-C chemokine mediated conditions.

Design, synthesis, and biological evaluation of substituted benzoate analogues of the selective nicotinic acetylcholine receptor antagonist, methyllycaconitine

The norditerpenoid alkaloid methyllycaconitine (MLA) acts as a competitive antagonist on the nicotinic acetylcholine receptor (nAChR) with a high preference for the neuronal α-bungarotoxin (αBgt)-sensitive nAChR over the muscle nAChR in mammals. MLA is thus a useful pharmacological tool. Furthermore, its efficient binding to insect nAChR indicates a high insecticidal potency. Within the complex hexacyclic structure of MLA, we envisaged a potential simple pharmacophore. This led to the design and synthesis of acyclic and monocyclic analogues of MLA. The biological activity of these derivatives at both neuronal nicotinic and muscarinic AChR was evaluated. Some of these structurally simple compounds, despite displaying a modest affinity for the nAChR, showed good specificity. We were able to show the importance of the 2-(methylsuccinimido)benzoate ester moiety and the E-ring of MLA. None of the analogues tested displayed any affinity for [3H]nicotine binding sites in brain membranes, indicating that α7-selectivity is already inherent in these simple structures. If higher affinities are to be obtained, however, there is a clear need for more structural information in the design of second generation simple analogues of MLA.

3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles

2-R2 -R4 -substituted-3-R3 -CO-1-[(C-attached-N-herteryl)-(Alk)n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.