54528-33-5

Upstream product

• 3731-52-0 3-Aminomethylpyridine 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 54528-10-8 1-(4-cyano-phenyl)-3-pyridin-3-ylmethyl-urea 
• 1229517-22-9 C₁₃H₁₂N₂O₃ 
• 53101-97-6 1-(4-chlorophenyl)-3-(pyridin-3-ylmethyl)urea 
• 36226-32-1 1-(pyridin-3-ylmethyl)urea 
• 41915-99-5 N,N-dimethyl-N′-(pyridin-3-ylmethyl)urea 

Relevant academic research and scientific papers

HYDRAZIDE COMPOUND AND KINASE INHIBITOR

The present invention aims to provide a novel compound capable of promoting cell proliferation in a cell culture (particularly three-dimensional cell culture). The hydrazide compound represented by the formula (I); wherein each symbol is as defined in DES

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

DIAZABICYCLOOCTANE DERIVATIVES COMPRISING A QUATERNERY AMMONIUM GROUP FOR USE AS ANTIBACTERIAL AGENTS

Compounds of Formula (I), pharmaceutical compositions comprising these compounds and their use in treating bacterial infection is disclosed.

4,5-DIHYDROISOXAZOLE DERIVATIVES AS NAMPT INHIBITORS

The present invention provides substituted 4,5-dihydroisoxazole derivatives of formula (I), which may be therapeutically useful, more particularly NAMPT inhibitors and in which R1 R2, Y, X, "Het" and "p" have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorder caused by an elevated level of nicotinamide phosphoribosyltransferase (NAMPT) in a mammal. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the substituted 4,5-dihydroisoxazole derivatives of formula (I) or a pharmaceutically acceptable salts or stereoisomers or N-oxide thereof.

CHEMOKINE RECEPTOR BINDING COMPOUNDS

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. Thesd compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).

3-Pyridylmethyl aryl urea rodenticides compositions

Rodenticidal compositions containing as the active ingredient novel 1-(3-pyridylmethyl)-3-(4'-substituted-phenyl or -naphthyl)ureas and their acid addition salts. The 4'-substituent may be nitro, cyano, trifluoromethyl, butyryl, thiocyano, alkylthio, phenylsulfonyl or diethylsulfonamide.

3-Pyridylmethyl aryl urea rodenticides

Novel 1-(3-pyridylmethyl)-3-(4'-substituted-phenyl or -naphthyl)-ureas and their acid addition salts. The 4'-substituent may be --NO2, --CN, --CF3, --C(O)R1, --SCN, SR2, --SO2 C6 H5 or --SO2 NR3 R4. These compounds are biologically active, and many are active rodenticides.