54535-06-7

Usage

Uses

Used in Pharmaceutical Industry:
Ethanol, 2,2'-[1,2-phenylenebis(oxy)]bis-, bis(4-methylbenzenesulfonate) is used as a solvent and stabilizer for various pharmaceutical products. Its ability to dissolve a wide range of substances and provide stability to formulations makes it a valuable component in the development of medications and other healthcare products.
Used in Cosmetic Industry:
In the cosmetic industry, Ethanol, 2,2'-[1,2-phenylenebis(oxy)]bis-, bis(4-methylbenzenesulfonate) is employed as a solvent and stabilizer to improve the performance and shelf life of cosmetic products. Its versatility in dissolving different ingredients and maintaining the stability of formulations contributes to the quality and effectiveness of cosmetics.
Used as a Synthesis Intermediate:
Ethanol, 2,2'-[1,2-phenylenebis(oxy)]bis-, bis(4-methylbenzenesulfonate) is used as an intermediate in the synthesis of other organic compounds. Its unique structure allows it to participate in various chemical reactions, making it a useful building block for creating a wide range of organic molecules.
Safety and Storage:
Ethanol, 2,2'-[1,2-phenylenebis(oxy)]bis-, bis(4-methylbenzenesulfonate) is generally considered to have low acute toxicity, but prolonged exposure can cause irritation to the skin and eyes. Therefore, it should be handled with care and according to proper safety protocols. To ensure its stability and effectiveness, it should be stored in a cool, dry place away from direct sunlight and sources of ignition.

Upstream product

• 10234-40-9 2,2'-(1,2-phenylenedioxy)diethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 120-80-9 benzene-1,2-diol 
• 52376-09-7 ethyl 2-<2-<(ethoxycarbonyl)methoxy>phenoxy>acetate 

Downstream Products

• 72167-36-3 6,7,9,10,12,13,15,16-octahydro-5,11,17-trioxa-8,14-diaza-benzocyclopentadecene-8,14-dicarboxylic acid dibenzyl ester 
• 72814-07-4 6,7,9,10,17,18,20,21-octahydro-5,11,16,22-tetraoxa-8,19-diaza-dibenzo[a,j]cyclooctadecene-8,19-dicarboxylic acid dibenzyl ester 
• 72814-03-0 Brenzcatechin-bis-(2-azidoethylether) 
• 133965-62-5 7-Benzyloxybenzo-13-crown-4 
• 124617-19-2 8,14-Bis-(toluene-4-sulfonyl)-7,8,9,10,13,14,15,16-octahydro-6H,12H-5,11,17-trioxa-8,14-diaza-benzocyclopentadecene 
• 124617-20-5 8,17-Bis-(toluene-4-sulfonyl)-7,8,9,10,12,13,16,17,18,19-decahydro-6H,15H-5,11,14,20-tetraoxa-8,17-diaza-benzocyclooctadecene 
• 119110-41-7 3,3'-<1,2-Phenylenbis(oxy)-2,1-ethandiyloxy>bis(2-naphthol)-dibenzylether 
• 121368-77-2 C₃₀H₄₀O₁₀P₂ 
• 85725-87-7 11-benzyloxymethyl-2,3-benzo-18-crown-6 
• 75863-81-9 2,2'-<1,2-Phenylenbis(oxy-2,1-ethandiyloxy)>bisphenol 
• 54533-83-4 benzo-10-aza-15-crown-5 
• 95796-22-8 C₂₄H₂₂O₈ 
• 110431-62-4 1,2-bis-(2-iodoethoxy)benzene 
• 157399-19-4 (1R,22S,24R,25S,26R)-25,26-Bis-benzyloxy-24-benzyloxymethyl-2,5,8,15,18,21,23-heptaoxa-tricyclo[20.2.2.0^9,14]hexacosa-9,11,13-triene 

Relevant academic research and scientific papers

Synthesis of chiral diaza 18-crown-6 ethers from chiral amines and molecular recognition of potassium and sodium salts of amino acids

A practical synthesis of chiral amine precursors 3 and 4 and chiral diaza 18-crown-6 ethers 5, 6 and 7 starting from chiral amines are reported. The molecular recognition of these chiral crown ethers for amino acids potassium and sodium salts has been characterized by UV-vis. The selectivity order is Phe>Thr>Ala. In the case of 6 the cavity of the macrocycle plays an important role in recognition.

Macrocyclic bis-urea receptor: Synthesis, crystal structure and phosphate binding properties

A macrocyclic bis-urea receptor (L1) and two acyclic bis-urea analogues (L2 and L3) have been synthesized. The crystal structure of L1 was obtained. The experimental results show that the receptor L1 has high selectivity to H2PO4 ?. Meanwhile, compared with the acyclic receptors L2 and L3, L1 has higher binding ability to H2PO4 ?. The results of density functional theory (DFT) calculations deepened our understanding on L1 conformations stability and its anion-binding property.

Rapid and scalable synthesis of chiral porphyrin cage compounds

An improved and scalable synthetic route to chiral porphyrin cage compounds, which will be used as catalytic machines for the encoding of information into polymers, has been developed. The porphyrin cage was made chiral by introducing one or two nitro gro

Formation and uses of europium complexes

The present invention provides a method of forming an oxidatively-stable aqueous Eu(II) complex by synthesizing ligands that coordinate to large, soft, electron rich metals like Eu(II). The invention also provides an oxidatively stable aqueous Eu(II) complex. The complex can be used for a variety of purposes some of which include, but are not limited to, in paramagnetic chemical exchange saturation transfer, as a medical diagnostic, as a semiconductor, and for use in forming materials.

Synthesis of enantiopure P-stereogenic diphosphacrowns using P-stereogenic secondary phosphines

A new synthetic route to enantiopure P-stereogenic benzodiphosphacrowns using a P-stereogenic secondary bisphosphine as the key building block is reported. Syntheses of the enantiomer and P-stereogenic crowns with various ring structures, as well as debor

Synthesis of monoazacrown ethers under phase-transfer catalysis

A procedure has been proposed for the synthesis of monoazacrown ethers by reaction of N-benzyldiethanolamine with oligo(ethylene glycol) bis-p-toluenesulfonates in a two-phase system aromatic hydrocarbon-50% aqueous alkali, followed by removal of the benzyl group by catalytic hydrogenolysis. The maximal yields of N-benzylaza-12-crown-4, -18-crown-6, and -21-crown-7 were achieved by adding 4-10 equiv of LiCl, BaBr2, and CsCl, respectively, to the reaction mixture, which probably indicated template effect. Pleiades Publishing, Ltd., 2012.

Synthesis and extraction properties of some lariat ethers derived from the spontaneously resolved guaifenesin, 3-(2-methoxyphenoxy)propane-1,2-diol

Capable of spontaneous resolution rac-3-(2-methoxyphenoxy)propane-1,2-diol, guaifenesin 1 has been proposed as a cheap and readily available enantiopure precursor for the synthesis of nonracemic crown ethers having ligating OAr and OMe arms (lariat ethers). The crowns studied failed to form stable host/guest complexes with amine hydrochloride salts; the effective complexation was achieved using hexafluorophosphate salts. Moderate enantiomeric recognition of R*NH2·HPF6 was achieved with the lariat ethers 11c. As a whole, the enantioselectivity of the extraction is inversely related to the extractive power of the lariat ether. ARKAT-USA, Inc.

Synthesis and evaluation of bis-thiazolium salts as potential antimalarial drugs

An innovative therapeutic approach based on the use of dicationic derivatives was previously designed to inhibit the biosynthesis of phosphatidylcholine in Plasmodium spp. Among these, bis-thiazolium salts were shown to block proliferation of the malaria

Oxidatively stable, aqueous europium(II) complexes through steric and electronic manipulation of cryptand coordination chemistry

A series of cryptands has been prepared and they demonstrate the relationship between oxidative stability of aqueous EuII and ligand properties (see figure). One of these EuII complexes is more stable than FeII in hemoglobin and appears to be the most oxidatively-stable aqueous EuII species known. The high stability of EuII is expected to enable the use of the unique magnetic and optical properties of this ion in vivo.

Synthesis of new chiral diaza 18-crown-6-ethers from chiral amines

Practical syntheses of versatile building blocks of crown ethers 1 and 2, chiral amine precursors 3-6 and chiral diaza 18-crown-6 ethers 7-12 are reported starting from chiral amines.